Abstract
Background Gestational gigantomastia is a rare and debilitating condition that is thought to
result from hormone hypersensitivity. Several definitions have been proposed using
breast weight and change in body mass index, but the breast growth is best summarized
as rapid, diffuse, and excessive.
Case We report a case of a 31-year-old woman with a history of infertility and cystic
fibrosis that developed pathologic breast growth during hormonal preparation for in vitro fertilization. Her serum laboratories were unremarkable, and she was medically managed
until 31 weeks of gestation. After delivery, she experienced rapid decrease in breast
size and was followed by plastic surgery with plan to allow spontaneous regression
with interval breast reduction
Conclusion We highlight a successful interdisciplinary medical management approach, which helped
to avoid a morbid, intrapartum breast reduction.
Keywords
gigantomastia - pregnancy - cystic fibrosis - infertility - medical management - interdisciplinary
