Interventional Treatment of Hepatic Metastases from Colorectal Cancer

Patrick D. Sutphin; Suvranu Ganguli

doi:10.1055/s-0040-171919

Seminars in Interventional Radiology, Inhaltsverzeichnis

Semin intervent Radiol 2020; 37(05): 492-498
DOI: 10.1055/s-0040-171919

Review Article

Interventional Treatment of Hepatic Metastases from Colorectal Cancer

Patrick D. Sutphin

¹Division of Interventional Radiology, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts

,

Suvranu Ganguli

²Division of Interventional Radiology, Department of Radiology, Boston Medical Center, Boston University Medical School, Boston, Massachusetts

› Institutsangaben

Abstract

Modern systemic therapies provide a significant survival benefit in metastatic colorectal cancer. Despite these advances, the durability of response remains limited and nearly all patients progress on systemic treatment. Colorectal liver metastases (CLM) develop in approximately half of patients with metastatic disease and contribute to mortality in most patients. In selected patients, surgical resection of hepatic metastases prolongs survival, indicating the benefits of the targeted treatment of CLM through alternate means. Minimally invasive interventional treatments offer the promise of treating CLM in a wider range of patients than those eligible for surgical resection. Thermal ablation and intra-arterial therapies, including chemoembolization and radioembolization, are commonly used in the treatment of CLM. Each of these treatment modalities will be discussed in detail with an emphasis on the available clinical data for each interventional treatment for CLM.

Keywords

colorectal cancer - colorectal liver metastases - ablation - radioembolization

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