An exclusively regioselective hydrocyanation of monofluoroalkenes has been developed,
with which a series of aliphatic quaternary α-fluoronitriles were synthesized in a
facile and efficient manner. This novel method is featured with mild conditions, good
functional groups compatibilities, and high reactivity.
Key words
quaternary α-fluoronitriles - hydrocyanation - monofluoroalkenes - cobalt catalysis
- radical