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CC BY-NC-ND 4.0 · Eur J Dent 2021; 15(03): 420-424
DOI: 10.1055/s-0040-1721311
Original Article

Comparative Remineralization Efficacy of Topical NovaMin and Fluoride on Incipient Enamel Lesions in Primary Teeth: Scanning Electron Microscope and Vickers Microhardness Evaluation

Safaa Shihabi
1   Department of Pediatric Dentistry, Faculty of Dentistry, Damascus University, Damascus, Syria
,
Salma AlNesser
1   Department of Pediatric Dentistry, Faculty of Dentistry, Damascus University, Damascus, Syria
,
John C. Comisi 
2   Department of Oral Rehabilitation, Restorative Dentistry, Medical University of South Carolina, James B. Edwards College of Dental Medicine, Charleston, United States
› Author Affiliations Funding This study received its financial support from Faculty of Dentistry, Damascus University.
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Abstract

Objective Evaluating the potential remineralization effect of NovaMin prophylaxis paste on artificial enamel lesions in primary teeth using Vickers microhardness and scanning electron microscope.

Materials and Methods Forty sound buccal and lingual surfaces of human primary canine teeth were randomly divided into two groups after creating artificially demineralized lesions (G1: NovaMin and G2: fluoride; 20 per group) and then treated with the respective remineralization agents. The remineralization cycle repeated twice daily for 10 days. The groups were evaluated with Vickers microhardness and scanning electron microscope before and after de/remineralization.

Results Statistically significant difference of microhardness was observed between demineralized enamel and remineralized enamel with group 1 and group 2 (p = 0.000 and p = 0.000, respectively). No statistically significant difference of microhardness was observed between two remineralized agents (p = 0.368).

Conclusion Within the limitation of this in vitro study, NovaMin enhances the remineralization process equally to fluoride.

Keywords

fluoride - NovaMin - vickers surface microhardness - scanning electron microscope - white spot lesions - hydroxycarbonate apatite


Publication History

Article published online:
15 December 2020

© 2020. European Journal of Dentistry. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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  • References

  • 1 Sarkis H, Ghaleb M, Dabbagh S. Harouny. White spot lesions: Resin infiltration technique. Int Arab J Dent 2017; 81: 10-14
    Google Scholar
  • 2 Townsend JA, Wells MH. Behavior guidance of the pediatric dental patient. In: Pediatric Dentistry. 2019. Elsevier; 352-357
    Google Scholar
  • 3 Roopa KB, Pathak S, Poornima P, Neena I. White spot lesions: a literature review. J Paediatr Dent 2015; 31: 1-7
    Google Scholar
  • 4 Arifa MK, Ephraim R, Rajamani T. Recent advances in dental hard tissue remineralization: a review of literature. Int J Clin Pediatr Dent 2019; 12 (02) 139-144
    CrossrefPubMedGoogle Scholar
  • 5 Soi S, Vinayak V, Singhal A, Roy S. Fluorides and their role in demineralisation and remineralisation. J Dent Sci Oral Rehabil 2013; 14: 19-21
    Google Scholar
  • 6 Ullah R, Zafar MS, Shahani N. Potential fluoride toxicity from oral medicaments: a review. Iran J Basic Med Sci 2017; 20 (08) 841-848
    PubMedGoogle Scholar
  • 7 Layer TM. Development of a fluoridated, daily-use toothpaste containing NovaMin technology for the treatment of dentin hypersensitivity. J Clin Dent 2011; 22 (03) 59-61
    PubMedGoogle Scholar
  • 8 Haghgoo R, Ahmadvand M, Moshaverinia S. Remineralizing effect of topical NovaMin and nano-hydroxyapatite on caries-like lesions in primary teeth. J Contemp Dent Pract 2016; 17 (08) 645-649
    CrossrefPubMedGoogle Scholar
  • 9 Gangwar A, Jha KK, Thakur J, Nath M. In Vitro evaluation of remineralization potential of novamin on artificially induced carious lesions in primary teeth using scanning electron microscope and vickers hardness. Indian J Dent Res 2019; 30 (04) 590-594
    CrossrefPubMedGoogle Scholar
  • 10 Walsh LJ. Contemporary technologies for remineralization therapies: a review. Int Dent SA 2009; 116: 6-16
    Google Scholar
  • 11 Jefferies SR. Advances in remineralization for early carious lesions: a comprehensive review. Compend Contin Educ Dent 2014; 35 (04) 237-243, quiz 244
    PubMedGoogle Scholar
  • 12 Cochrane NJ, Cai F, Huq NL, Burrow MF, Reynolds EC. New approaches to enhanced remineralization of tooth enamel. J Dent Res 2010; 89 (11) 1187-1197
    CrossrefPubMedGoogle Scholar
  • 13 De Menezes Oliveira MAH, Torres CP, Gomes-Silva JM. et al. Microstructure and mineral composition of dental enamel of permanent and deciduous teeth. Microsc Res Tech 2010; 73 (05) 572-577
    PubMedGoogle Scholar
  • 14 Şakar-Deliormanli A, Güden M. Microhardness and fracture toughness of dental materials by indentation method. J Biomed Mater Res B Appl Biomater 2006; 76 (02) 257-264
    CrossrefPubMedGoogle Scholar
  • 15 Creanor SL, Awawdeh LA, Saunders WP, Foye RH, Gilmour WH. The effect of a resin-modified glass ionomer restorative material on artificially demineralised dentine caries in vitro . J Dent 1998; 26 (5-6) 527-531
    CrossrefPubMedGoogle Scholar
  • 16 Wang Y, Mei L, Gong L. et al. Remineralization of early enamel caries lesions using different bioactive elements containing toothpastes: an in vitro study. Technol Health Care 2016; 24 (05) 701-711
    CrossrefPubMedGoogle Scholar
  • 17 Manoharan V, Kumar RK, Sivanraj AK, Arumugam SB. Comparative evaluation of remineralization potential of casein phosphopeptide-amorphous calcium fluoride phosphate and novamin on artificially demineralized human enamel: an in vitro study. Contemp Clin Dent 2018; 9 (Suppl. 01) S58-S63
    CrossrefPubMedGoogle Scholar
  • 18 Krishnan G, George S, Anandaraj S, John SA, Mathew V, Shanavas NM. Efficacy of four remineralizing agents on primary teeth: in vitro evaluation using microhardness testing and quantitative light-induced fluorescence. Pediatr Dent 2017; 39 (03) 233-237
    PubMedGoogle Scholar
  • 19 Aras A, Celenk S, Dogan MS, Bardakci E. Comparative evaluation of combined remineralization agents on demineralized tooth surface. Niger J Clin Pract 2019; 22 (11) 1546-1552
    CrossrefPubMedGoogle Scholar
  • 20 Gjorgievska E, Nicholson JW. Prevention of enamel demineralization after tooth bleaching by bioactive glass incorporated into toothpaste. Aust Dent J 2011; 56 (02) 193-200
    CrossrefPubMedGoogle Scholar
  • 21 Khijmatgar S, Reddy U, John S, Badavannavar AN, D. Souza T. Is there evidence for Novamin application in remineralization?: a systematic review. J Oral Biol Craniofac Res 2020; 10 (02) 87-92
    CrossrefPubMedGoogle Scholar
  • 22 Hench LL, Andersson Ö. Bioactive Glasses: An Introduction to Bioceramics. 1993. World Scientific; 41-62
    CrossrefGoogle Scholar