Kardiologie up2date 2015; 11(04): 212-216
DOI: 10.1055/s-0041-108636
Hotline – Koronare Herzerkrankung und Atherosklerose
© Georg Thieme Verlag KG Stuttgart · New York

Update Atherogenese 2015

Ingo Hilgendorf
Andreas Zirlik
Further Information

Publication History

Publication Date:
22 December 2015 (online)


Atherogenesis and its clinical sequelae account for most deaths world-wide. It results from a distorted lipid metabolism and imbalanced immune response. In this review we discuss common and emerging risk factors that lead to plaque formation, the biology behind it, and recent advances and challenges in atherosclerosis therapy.