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Homeopathic Remedies in COVID-19: Prognostic Factor ResearchFunding Indian Government infrastructure was used. No special funding was provided as all the contributors are full-time staff employed by the Government of NCT of Delhi.
Background/Objective Coronavirus disease 2019 (COVID-19) is a new disease; its clinical profile and natural history are evolving. Each well-recorded case in homeopathic practice is important for deciding the future course of action. This study aims at identifying clinically useful homeopathic remedies and their prescribing symptoms using the prognostic factor research model.
Methods This was an open-label, multi-centric, observational study performed from April 2020 to July 2020 at various public health care clinics. The data were collected prospectively from clinical practice at integrated COVID-19 care facilities in India. Good-quality cases were selected using a specific set of criteria. These cases were analyzed for elucidating prognostic factors by calculating the likelihood ratio (LR) of each frequently occurring symptom. The symptoms with high LR values (>1) were considered as prescribing indications of the specific remedy.
Results Out of 327 COVID-19 cases reported, 211 met the selection criteria for analysis. The most common complaints were fatigue, sore throat, dry cough, myalgia, fever, dry mouth and throat, increased thirst, headache, decreased appetite, anxiety, and altered taste. Twenty-seven remedies were prescribed and four of them—Arsenicum album, Bryonia alba, Gelsemium sempervirens, and Pulsatilla nigricans—were the most frequently used. A high LR was obtained for certain symptoms, which enabled differentiation between the remedies for a given patient.
Conclusion Homeopathic medicines were associated with improvement in symptoms of COVID-19 cases. Characteristic symptoms of four frequently indicated remedies have been identified using prognostic factor research, findings that can contribute to accurate homeopathic prescribing during future controlled research in COVID-19.
• Clinical data were collected from contemporary homeopathic practice in integrated COVID-19 care centers in India.
• Prescribing indications of the four most frequently used homeopathic medicines, i.e., Arsenicum album, Bryonia alba, Gelsemium sempervirens and Pulsatilla nigricans, were identified using prognostic factor research.
• The findings may improve the accuracy of future homeopathic prescribing of COVID-19 patients.
This study was conducted under the overall guidance of author R.K.M., who contributed toward planning, training of investigators, study design, and critical evaluation of data and manuscript, besides ensuring logistic support. Cases were treated and data sheets were completed by all co-authors. These authors also contributed toward critical review of the spreadsheet, data analysis, and subsequent review. Authors A.M., M.G., and B.S. helped in the development of study design, statistical analysis, manuscript writing, and data collection coordination. All authors are responsible for and agreed to the content of the manuscript.
Received: 30 October 2020
Accepted: 30 November 2020
30 April 2021 (online)
© 2021. Faculty of Homeopathy. This article is published by Thieme.
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