CC BY-NC-ND 4.0 · Homeopathy 2021; 110(04): 283-291
DOI: 10.1055/s-0041-1726008

Telomere and Telomerase: Biological Markers of Organic Vital Force State and Homeopathic Treatment Effectiveness

1   School of Medicine, University of São Paulo, São Paulo, Brazil
› Author Affiliations


Background Philosophical–scientific correlations described in previous studies suggest that the genome can be the biological representation of the vital force, whilst the disease-promoting epigenetic alterations would be the biological representation of the chronic miasmas. In this study, we expand the functional correlation between vital force and chromosomes, describing the mechanism of action of the telomere–telomerase complex in the context of physiological balance.

Aims The aim of the work is to study the role of the telomere–telomerase complex in cell vitality, biological aging, and the health-disease process, with the goal of proposing the use of telomere length as a biomarker of the vital force state and the effectiveness of homeopathic treatment.

Results Similar to the vital force, telomere length and telomerase enzyme activity play an important role in maintaining cellular vitality, biological longevity, and physiological homeostasis. Telomere shortening functions as a biomarker of vital imbalance and is associated with numerous diseases and health disorders. On the other hand, health-promotion practices neutralize the pathological shortening of the telomeres, acting therapeutically in diseases or age-dependent health disorders.

Conclusions As a hypothetical biomarker of the vital force state, an intra-individual analysis of the mean leukocyte telomere length before, during, and after homeopathic treatment can be used as a biomarker of therapeutic effectiveness.


• The homeopathic vital force is a philosophical non-material substrate, theoretically responsible for maintaining the physiological homeostasis and the body's health state.

• The body's vital functions are controlled by biochemical information contained in the cell genome (exome plus epigenome).

• In line with the similarity of existing characteristics and properties, we suggested that the cell genome can be considered as the biological representation of the organic vital force.

• Telomere length plays an important role in maintaining cellular vitality, biological longevity, and physiological homeostasis.

• Analysis of the intra-individual telomere length might be used as a biological marker of organic vital force state and of homeopathic treatment effectiveness.

Publication History

Received: 03 November 2020

Accepted: 03 December 2020

Article published online:
17 May 2021

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