Aspiration Thrombectomy for Acute Limb Ischemia: A Single Center Experience

Background: Acute lower-extremity ischemia (ALI) is associated with high in-hospital amputation rates of 10%–30%, 1-year mortality rates of 15%–20%, and low amputation-free survival rates of 50%–65%. Although catheter-directed thrombolysis (CDT) is associated with a lower morbidity rate and is as effective as surgery for stage I and IIa ALI, it takes substantial time to be effective. The Indigo System (Penumbra, inc) is designed for aspiration thromboembolectomy available from 3 f to 8 f in size. The size-matched “separator” allows the catheter to be cleared of occlusive material without catheter removal from the area of thrombus. It has a pump-driven vacuum for consistent aspiration.r preliminary results of this device in the treatment of ali have been recently published. We want to report our single center experience with percutaneous aspiration thrombectomy (pat) as a first line treatment for acute lower limb ischemia (ALI). Method(s): Twenty-one patients who underwent pat for ali from March 2017 to June 2018 were included. The primary end-point was complete thrombus aspiration with return to patency of the target vessel. Adjunctive treatment for underlying stenosis or occlusion was not considered indicating technical failure, while the use of additional treatment for thrombus removal was considered as a technical failure. Result(s): The technical success was obtained in 18/21 patients (85.7%); 2 of the remaining 3 patients required additional treatment for thrombus removal and in 1 the pat failed to restored patency and the patient underwent open surgical treatment. No complications related to pad were reported. Conclusion(s): The technical success was obtained in 18/21 patients (85.7%); 2 of the remaining 3 patients required additional treatment for thrombus removal and in 1 the pat failed to restored patency and the patient underwent open surgical treatment. No complications related to pad were reported.

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Artikel online veröffentlicht:
11. Mai 2021