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J Neurol Surg B Skull Base 2022; 83(04): 443-450
DOI: 10.1055/s-0041-1731033
Original Article

A Volumetric Study of the Corpus Callosum in the Turkish Population

Handan Soysal
1   Department of Anatomy, Faculty of Dentistry, Ankara Yıldırım Beyazıt University, Ankara, Turkey
,
Niyazi Acer
2   Department of Anatomy, Faculty of Medicine, Arel University, İstanbul, Turkey
,
Meltem Özdemir
3   Department of Radiology, Dışkapı Yıldırım Beyazıt Health Application and Research Center, Medical Sciences University, Ankara, Turkey
,
Önder Eraslan
3   Department of Radiology, Dışkapı Yıldırım Beyazıt Health Application and Research Center, Medical Sciences University, Ankara, Turkey
› Author Affiliations Funding None.
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Abstract

Objective The aim of this study is to measure the average corpus callosum (CC) volume of healthy Turkish humans and to analyze the effects of gender and age on volumes, including the genu, truncus, and splenium parts of the CC.

Patients and Methods Magnetic resonance imaging brain scans were obtained from 301 healthy male and female subjects, aged 11 to 84 years. The median age was 42 years (min–max: 11–82) in females and 49 years (min–max: 12–84) in males. Corpus callosum and its parts were calculated by using MRICloud. CC volumes of each subject were compared with those of the age and gender groups.

Results All volumes of the CC were significantly higher in males than females. All left volumes except BCC were significantly higher than the right volumes in both males and females. The oldest two age groups (50–69 and 70–84 years) were found to have higher bilateral CC volumes, and bilateral BCC volumes were also higher than in the other two age groups (11–29 and 30–49 years).

Conclusion The results suggest that compared with females/males, females have a faster decline in the volume of all volumes of the CC. We think that quantitative structural magnetic resonance data of the brain is vital in understanding human brain function and development.

Keywords

corpus callosum - magnetic resonance imaging - volumetry - Turkish population

Note

Research was conducted on human participants. All procedures performed in this study comply with the ethical standards of the institution. Prior to this review, the approval of the institutional review board was obtained. This study was approved by the Clinical Research Ethics Committee of Dışkapı Yıldırım Beyazıt Training and Research Hospital. A signed form was obtained from each participant indicating that the patient was informed and approved.




Publication History

Received: 04 December 2020

Accepted: 07 May 2021

Article published online:
30 June 2021

© 2021. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 

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