Abstract
Magnetic resonance imaging (MRI) scans for children are a challenge for anesthesiologists
since the child must be sedated enough to stand still. But anesthetic drugs used for
sedation might have serious side effects and monitorization resources and accessibility
to the patient during MRI scan is limited. We retrospectively examined 977 pediatric
patients' files who had MRI scans in our hospital. We observed that children received
one of the four combinations of anesthetic drugs: group 1 received midazolam, propofol,
and ketamine; group 2 received midazolam and ketamine; group 3 received midazolam
and thiopental; and group 4 received midazolam and propofol combination for sedation.
The patients in group 1 had significantly higher vomiting rates than the patients
in group 4 (p = 0.005). We observed bronchospasm in patients in group 1 (p = 0.006) and group 3 (p = 0.001), more than in patients in group 4. Nausea and vomiting ratios were lower
in group 4. In patients with nausea and vomiting within a week after the procedure,
statistically significant lower neutrophil–lymphocyte ratio values (p = 0.012) were observed. All four anesthetic combinations used in the trial provided
safe anesthesia for the children, during the MRI scan. The anesthetic choice must
be made according to the procedure time and patient's comorbidities. In this trial,
we observed minimum side effects with midazolam and propofol combination.
Keywords
magnetic resonance imaging - anesthesia - pediatric patients - neutrophil–lymphocyte
ratio
