Open Access
CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2007; 28(01): 30-32
DOI: 10.1055/s-0041-1733202
Case Report

Rare Association of Transient Myeloprolifierative Disorder and Imperforate Anus in a Neonate with Trisomy 21

Authors

  • Dinesh Sarda

    Department of Paediatric surgery, L.T.M.M.C & Gen. Hospital, Mumbai-22, India
  • Paras Kothari

    Department of Paediatric surgery, L.T.M.M.C & Gen. Hospital, Mumbai-22, India
  • Bharati Kulkarni

    Department of Paediatric surgery, L.T.M.M.C & Gen. Hospital, Mumbai-22, India
  • Nagesh Dasarwar

    Department of Paediatrics, L.T.M.M.C & Gen. Hospital, Mumbai-22, India
Preview Container


Publication History

Article published online:
23 March 2022

© 2007. Indian Society of Medical and Paediatric Oncology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/.)

Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India

 
  • References

  • 1 Black CT, Sherman JO. The association of low imperforate anus and Down’s syndrome. J Pediatr Surg. 1989;24:92-4.
  • 2 Shah AA, Mehta AA, Desai M and shah AV. et al. Down Syndrome with Transient Myeloid Leukemia and Urological Abnormality. Ind Pediatrics 2003;40:155-158.
  • 3 Cushing T. Clericuzio CL, Wilson, CS, et al. Risk for leukemia in infants without down syndrome who have transient myeloproliferative disorder. J. Pediatr 2006;148:687-689
  • 4 Verma M, Rawat P, Das S et al. Congenital acute myeloid leukemia in a case of Down syndrome. A case report. Ind J Hemat Blood Transf 2001;19:110- 111.
  • 5 Awasthi A, Das R, Varma N et al. Hematological disorders in Down syndrome: ten-year experience at a Tertiary Care Centre in North India. Pediatr Hematol Oncol. 2005;22:507-12.
  • 6 Hasle H, Lund B, Nyvold CG et al. WT1 gene expression in children with Down syndrome and transient myeloproliferative disorder. Leuk Res. 2006;30:543-6.
  • 7 Shen JJ, Williams BJ, Zipursky A et al. Cytogenetic and molecular studies of Down syndrome individuals with leukemia. Am J Hum Genet 1995;56:915-925.
  • 8 Suarez CR, Le Beau MM, Silberman S et al. Acute megakaryoblstic leukemia in Down syndrome: report of a case and review of cytogenetic findings. Med Pediatr Oncol 1985;13:225-231.
  • 9 Carpenter E, Valverde-Garduno V, Sternberg A et al. GATA1 mutation and trisomy 21 are required only in haematopoietic cells for development of transient myeloproliferative disorder. Br J Haematol. 2005;128:548-51.
  • 10 Golub TR, Arceci RJ. Acute myelogenous Leukamia. Principles and Practice of Pediatric oncology. 4th edition. Edited by Pizzo Philip A, Poplack David G. Lippincott Williams and Wilkins 1989;pp565-66.
  • 11 Al-Kasim F, Doyle JJ, Massey GV et al. Incidence and treatment of potentiallly lethal diseases in transient leukaemia of down synbdrome. Pediatric Oncology Group study. J Pediatr Hematol Oncol 2002;24:9-13.
  • 12 Bennett C, Hsu K, Look AT. Myeloid Leukaemia, Myelodysplasia, and myeloproliferative Disease in children. Hematology of infancy and childhood. Sixth edition. WB Saunders Company. 2003;1185
  • 13 Urioste M, Martinez-Frias ML. Anorectal anomalies and Down syndrome. Am J Med Genet. 1989;34:330-1.
  • 14 Torres R, Levitt MA, Tovilla JM et al. Anorectal malformations and Down’s syndrome. J Pediatr Surg. 1998;33:194-7.