Semin Musculoskelet Radiol 2021; 25(06): 735-744
DOI: 10.1055/s-0041-1735475
Review Article

Orthobiologics: Diagnosis and Treatment of Common Tendinopathies

Katherine D. Van Schaik
1   Department of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts
,
2   University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin
3   Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin
› Author Affiliations

Abstract

Orthobiologics, including platelet-rich plasma, prolotherapy, and mesenchymal stem cells, are seeing increasing use in the treatment of osteoarthritis (OA), muscle injury, and tendinopathy. This article reviews the biology and applications of orthobiologics in tendons, muscles, and joints, and focuses on platelet-rich plasma (PRP). Clinical evidence-based literature related to the use of PRP in the treatment of rotator cuff injury, lateral epicondylosis, Achilles tendinopathy, plantar fasciitis, knee OA, and acute muscle injury are discussed.



Publication History

Article published online:
22 December 2021

© 2021. Thieme. All rights reserved.

Thieme Medical Publishers, Inc.
333 Seventh Avenue, 18th Floor, New York, NY 10001, USA