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CC BY-NC-ND 4.0 · J Neurol Surg Rep 2021; 82(03): e36-e37
DOI: 10.1055/s-0041-1736160
Skull Base Oncology Case Series

Induction Chemotherapy for Orbit Preservation in Sinonasal Squamous Cell Carcinoma

Gabriela Lilly
1   Department of Otolaryngology-Head and Neck Surgery, Oregon Health & Science University, Portland, Oregon, United States
,
Mathew Geltzeiler
1   Department of Otolaryngology-Head and Neck Surgery, Oregon Health & Science University, Portland, Oregon, United States
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Abstract

Sinonasal squamous cell carcinoma (SNSCC) is a rare and aggressive malignancy which often presents at an advanced stage. The gold-standard treatment includes negative-margin surgical resection plus adjuvant therapy. In cases of orbital invasion, surgery requires orbital exenteration which can carry significant morbidity and result in decreased quality of life. In selected patients, induction chemotherapy (IC) can allow for orbit preservation without compromising oncologic outcomes. The available literature will be briefly discussed.

Keywords

sinonasal squamous cell carcinoma - orbit preservation - orbital exenteration - induction chemotherapy


Publication History

Received: 26 April 2021

Accepted: 13 July 2021

Article published online:
29 September 2021

© 2021. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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