CC BY-NC-ND 4.0 · Indian J Radiol Imaging 2021; 31(03): 693-696
DOI: 10.1055/s-0041-1736162
Case Report

Case of the Very Rare Gallbladder Paraganglioma

Shukla Shreya
1   Department of Radio-Diagnosis, Jaslok Hospital and Research Centre, Mumbai, Maharashtra, India
,
Ritu Kashikar
1   Department of Radio-Diagnosis, Jaslok Hospital and Research Centre, Mumbai, Maharashtra, India
,
Sinhasan R. Shraddha
1   Department of Radio-Diagnosis, Jaslok Hospital and Research Centre, Mumbai, Maharashtra, India
,
Desai Shrinivas
1   Department of Radio-Diagnosis, Jaslok Hospital and Research Centre, Mumbai, Maharashtra, India
› Author Affiliations
Funding None.

Abstract

Gallbladder paraganglioma is a very rare condition, and only a few cases have been reported in the literature. Herein, we present and discuss the clinical and radiological findings of a 72-year-old woman who complained of heaviness, pain, and on and off watery discharge from the left ear for 1 year and reduced hearing in both ears. She was thoroughly investigated radiologically where multiple paragangliomas were found with the discovery of the very rare gallbladder paraganglioma. There is a need to realize the importance of thorough radiological evaluation in cases of head and neck paraganglioma to look for more such lesions in the body for early identification of patients with familial paraganglioma syndromes. With this practice, gene mutation carriers can be identified early in the course of their disease and brought to surgical attention before their disease becomes extensive and potentially life-threatening.



Publication History

Article published online:
06 October 2021

© 2021. Indian Radiological Association. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India

 
  • References

  • 1 Lack EE. Paraganglioma. In: Sternberg SS. ed. Diagnostic Surgical Pathology. 2nd ed.. New York, NY: Raven Press; 1994: 599-621
  • 2 Rosai J. Adrenal gland and other paraganglia. In: Rosai J. ed. Ackerman's Surgical Pathology. 8th ed.. St. Louis: Mosby; 1996: 1015-1058
  • 3 Duncan AW, Lack EE, Deck MF. Radiological evaluation of paragangliomas of the head and neck. Radiology 1979; 132 (01) 99-105
  • 4 Oztas M, Ersoz N, Ozerhan I. et al. Gallbladder paraganglioma: report of a rare case. Gülhane Tip Derg 2015; 57: 73-75
  • 5 Pommier RF, Vetto JT, Billingsly K, Woltering EA, Brennan MF. Comparison of adrenal and extraadrenal pheochromocytomas. Surgery 1993; 114 (06) 1160-1165 , discussion 1165–1166
  • 6 Linnoila RI, Keiser HR, Steinberg SM, Lack EE. Histopathology of benign versus malignant sympathoadrenal paragangliomas: clinicopathologic study of 120 cases including unusual histologic features. Hum Pathol 1990; 21 (11) 1168-1180
  • 7 Miller TA, Weber TR, Appelman HD. Paraganglioma of the gallbladder. Arch Surg 1972; 105 (04) 637-639
  • 8 Young AL, Baysal BE, Deb A, Young Jr WF. Familial malignant catecholamine-secreting paraganglioma with prolonged survival associated with mutation in the succinate dehydrogenase B gene. J Clin Endocrinol Metab 2002; 87 (09) 4101-4105
  • 9 Magliulo G, Zardo F, Varacalli S, D'Amico R. Multiple paragangliomas of the head and neck. An Otorrinolaringol Ibero Am 2003; 30 (01) 31-38
  • 10 Grufferman S, Gillman MW, Pasternak LR, Peterson CL, Young Jr WG. Familial carotid body tumors: case report and epidemiologic review. Cancer 1980; 46 (09) 2116-2122
  • 11 Mehra S, Chung-Park M. Gallbladder paraganglioma: a case report with review of the literature. Arch Pathol Lab Med 2005; 129 (04) 523-526