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CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2021; 42(05): 506-509
DOI: 10.1055/s-0041-1736210
Case Report with Review of Literature

Chondrosarcoma of the Nasal Septum—A Rare Subsite: Case Report with Review of Literature

Nidhi Gupta 
1   Department of Radiation Oncology, Government Medical College and Hospital, Chandigarh, India
,
Awadhesh Kumar Pandey
1   Department of Radiation Oncology, Government Medical College and Hospital, Chandigarh, India
,
Kislay Dimri
1   Department of Radiation Oncology, Government Medical College and Hospital, Chandigarh, India
,
Surinder K Singhal
2   Department of ENT, Government Medical College and Hospital, Chandigarh, India
,
Neeraj Rathee
1   Department of Radiation Oncology, Government Medical College and Hospital, Chandigarh, India
,
Shalu Naryal
1   Department of Radiation Oncology, Government Medical College and Hospital, Chandigarh, India
,
Pooja Sharma
3   Department of Pathology, Government Medical College and Hospital, Chandigarh, India
,
Amitabh Kumar Upadhyay
4   Department of Medical Oncology, Tata Main Hospital, Jamshedpur, Jharkhand, India
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Abstract

Chondrosarcomas are the second most common primary malignant bone tumors. Head and neck chondrosarcomas constitute less than 10% of these tumors, rarely arising from the nasal septum. These are locally aggressive malignant tumors arising from the cartilaginous framework of the nasal septum. Rarity of the tumor coupled with nonspecific symptoms makes it a diagnostic dilemma. Diagnosis requires endoscopy, radiology, and final histopathology for confirmation. Treatment is mainly surgical, requiring complete surgical excision with clear margins. Radiation has a role in unresectable tumors or for tumors with positive margins after surgery. Survival depends on the grade of tumor that predicts the metastatic potential of the tumor. We present a rare case of chondrosarcoma arising from the nasal septum in a 29-year-old young female presenting with complaints of nasal obstruction. Computed tomography was suggestive of a calcified cartilaginous tumor arising from the nasal septum. Endoscopic excision was done and postoperative histopathology showed grade II chondrosarcoma with clear margins. No adjuvant treatment was given to our patient and 2 years post-excision patient is disease free.

To conclude, chondrosarcoma of the nasal septum is a rare tumor, with nonspecific symptoms. Surgery with clear margins remains the treatment of choice. Prognosis depends on the extent of tumor at presentation, resection margins, and grade of tumor.

Keywords

malignant - cartilage - head and neck - grade - treatment

Declaration of Patient Consent

Witten informed consent was taken from the patient.




Publication History

Article published online:
24 December 2021

© 2021. Indian Society of Medical and Paediatric Oncology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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