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CC BY-NC-ND 4.0 · Journal of Health and Allied Sciences NU 2022; 12(02): 214-216
DOI: 10.1055/s-0041-1736280
Case Report

Vitamin D Supplementation in Sarcoidosis: A Double-Edged Sword

Rishikesh Chandran
1   Department of General Medicine, K.S. Hegde Medical Academy, Mangalore, Karnataka, India
,
Lakshmi Nagendra 
2   Department of Endocrinology, K.S. Hegde Medical Academy, Mangalore, Karnataka, India
,
Shrikrishna Acharya
2   Department of Endocrinology, K.S. Hegde Medical Academy, Mangalore, Karnataka, India
,
Giridhar Belur Hosmane
3   Department of Pulmonology, K.S. Hegde Medical Academy, Mangalore, Karnataka, India
,
Vijith Shetty
4   Department of Oncology, K.S. Hegde Medical Academy, Mangalore, Karnataka, India
,
Adithi Kellarai
1   Department of General Medicine, K.S. Hegde Medical Academy, Mangalore, Karnataka, India
,
Bhagavan KR
5   Department of General Surgery, K.S. Hegde Medical Academy, Mangalore, Karnataka, India
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Abstract

Sarcoidosis is complicated by disordered vitamin D and calcium metabolism, which has important implications on disease activity and bone health. Although the majority of the patients with sarcoidosis are typically deficient in 25-hydroxyvitamin D, repletion of vitamin D is controversial in light of the hypercalcemia risk. Presently, there are no clear guidelines regarding vitamin D supplementation as a part of osteoporosis prevention in patients with vitamin D deficiency and sarcoidosis. We report a patient with sarcoidosis who presented with severe hypercalcemia following vitamin D supplementation and review the debated role of vitamin D supplementation in vitamin D-deficient sarcoid patients.

Keywords

Sarcoidosis - vitamin D deficiency - hypercalcemia

Note

Informed consent was obtained from all individual participants included in the study. All procedures performed in the study involving human participants were in accordance with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.




Publication History

Article published online:
24 October 2021

© 2021. Nitte (Deemed to be University). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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