Scrotal Lipoblastoma with Radiological and Histological Correlation

Abstract

Lipoblastomas are rare benign mesenchymal tumors comprised primarily mature adipocytes, which are most commonly found in infants and children younger than 3 years. They are usually found in the extremities, trunk, head, neck, and retroperitoneum, although cases occurring in the scrotum have been reported. Due to its rarity, there is a relative paucity of literature describing its imaging and management. We present a rare case of a scrotal lipoblastoma, and discuss the current imaging strategies to differentiate this adipocytic tumor from other more common paratesticular masses, including aggressive neoplasms such as rhabdomyosarcomas. Knowledge of the radiological appearance of lipoblastoma can provide the correct diagnosis and prevent unnecessary orchiectomy.

Keywords

adipocytic tumor - lipoblastoma - mesenchymal tumors - paratesticular mass - rhabdomyosarcoma

Declaration of Patient Consent

The authors certify that they have obtained all appropriate patient consent forms. In the form, the patient(s) has/have given his/her/their consent for his/her/their images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed.

Financial Support and Sponsorship

Nil.

Publication History

Article published online:
13 November 2021

• References

• 1 Abdul-Ghafar J, Ahmad Z, Tariq MU, Kayani N, Uddin N. Lipoblastoma: a clinicopathologic review of 23 cases from a major tertiary care center plus detailed review of literature. BMC Res Notes 2018; 11 (01) 42
• 2 Chung EB, Enzinger FM. Benign lipoblastomatosis. An analysis of 35 cases. Cancer 1973; 32 (02) 482-492
• 3 Yada K, Ishibashi H, Mori H, Shimada M. Intrascrotal lipoblastoma: report of a case and the review of literature. Surg Case Rep 2016; 2 (01) 34
• 4 Pereira-Lourenço MJ, Vieira-Brito D, Peralta JP, Castelo-Branco N. Intrascrotal lipoblastoma in adulthood. BMJ Case Rep 2019; 12 (12) e231320
• 5 Hanine D, Aboulam Z, Bouljrouf J, Kisra M. Para testicular lipoblastoma in children (about an exceptional case). Int J Med Res 2018; 3: 101-103
• 6 Akbar SA, Sayyed TA, Jafri SZH, Hasteh F, Neill JSA. Multimodality imaging of paratesticular neoplasms and their rare mimics. Radiographics 2003; 23 (06) 1461-1476
• 7 Ahmed HU, Arya M, Muneer A, Mushtaq I, Sebire NJ. Testicular and paratesticular tumours in the prepubertal population. Lancet Oncol 2010; 11 (05) 476-483
• 8 Annam A, Munden MM, Mehollin-Ray AR, Schady D, Browne LP. Extratesticular masses in children: taking ultrasound beyond paratesticular rhabdomyosarcoma. Pediatr Radiol 2015; 45 (09) 1382-1391
• 9 Moholkar S, Sebire NJ, Roebuck DJ. Radiological-pathological correlation in lipoblastoma and lipoblastomatosis. Pediatr Radiol 2006; 36 (08) 851-856
• 10 Sangüesa C, Veiga D, Llavador M, Serrano A. Testicular tumours in children: an approach to diagnosis and management with pathologic correlation. Insights Imaging 2020; 11 (01) 74
• 11 Burt AM, Huang BK. Imaging review of lipomatous musculoskeletal lesions. SICOT J 2017; 3: 34
• 12 Hayashida M, Yano A, Nagamoto S, Sakaguchi K, Okaneya T, Urakami S. Intrascrotal hibernoma mimicking liposarcoma: a case study. Urol Case Rep 2020; 32: 101206
• 13 Secil M, Bertolotto M, Rocher L. et al; European Society of Urogenital Radiology Scrotal Imaging Subcommittee. Imaging features of paratesticular masses. J Ultrasound Med 2017; 36 (07) 1487-1509
• 14 Aigner F, De Zordo T, Pallwein-Prettner L. et al. Real-time sonoelastography for the evaluation of testicular lesions. Radiology 2012; 263 (02) 584-589
• 15 Gupta P, Potti TA, Wuertzer SD, Lenchik L, Pacholke DA. Spectrum of fat-containing soft-tissue masses at MR imaging: the common, the uncommon, the characteristic, and the sometimes confusing. Radiographics 2016; 36 (03) 753-766
• 16 Tomihama RT, Lindskog DM, Ahrens W, Haims AH. Hibernoma: a case report demonstrating usefulness of MR angiography in characterizing the tumor. Skeletal Radiol 2007; 36 (06) 541-545
• 17 Jalles F, Pinto PL, Martins AP, Goncalves M. Lipoblastoma of the abdominal wall. J Pediatr Surg Case Rep 2019; 50: 101203
• 18 Steckman D, Zide B, Greco MA, Rivera R, Blei F. Lipoblastoma of infancy mimicking hemangioma of infancy. Arch Facial Plast Surg 2005; 7 (05) 326-330
• 19 Dy JS, Fuchs A, Palmer LS. Benign intrascrotal lipoblastoma in a child. Urology 2007; 70 (02) 372.e1-372.e2