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CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2021; 42(04): 385-389
DOI: 10.1055/s-0041-1736682
Case Report with Review of Literature

Orbital Metastasis as Initial Clinical Presentation in a Patient of Hepatocellular Carcinoma – A Rare Case with Review of Literature

Sakshi Rana
1   Department of Radiotherapy, Regional Cancer Centre, Postgraduate Institute of Medical Education and Research, Chandigarh, India
,
Divya Khosla
1   Department of Radiotherapy, Regional Cancer Centre, Postgraduate Institute of Medical Education and Research, Chandigarh, India
,
Kannan Periasamy
1   Department of Radiotherapy, Regional Cancer Centre, Postgraduate Institute of Medical Education and Research, Chandigarh, India
,
Rakesh Kapoor
1   Department of Radiotherapy, Regional Cancer Centre, Postgraduate Institute of Medical Education and Research, Chandigarh, India
,
Sunny Bhardwaj
2   Department of Cytology and Gynecologic Pathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
,
Renu Madan
1   Department of Radiotherapy, Regional Cancer Centre, Postgraduate Institute of Medical Education and Research, Chandigarh, India
,
Shikha Goyal
1   Department of Radiotherapy, Regional Cancer Centre, Postgraduate Institute of Medical Education and Research, Chandigarh, India
,
Arvind Rajwanshi
2   Department of Cytology and Gynecologic Pathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
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Abstract

Orbital metastasis, as the initial clinical presentation in hepatocellular carcinoma (HCC), is a rare manifestation. A 66-year-old male patient presented with a history of protrusion of the eyeballs, double vision, and swelling over the left side of the head for 8 months. Magnetic resonance imaging of the brain with orbit revealed a heterogeneous lesion in the left frontal lobe causing its destruction with intraorbital and intracranial extension. Triphasic contrast-enhanced computed tomography was suggestive of multiple hypodense areas in both lobes of the liver. Tissue diagnosis from the liver was suggestive of HCC. A diagnosis of multifocal HCC with orbital metastasis was made. The patient was treated with palliative radiotherapy and sorafenib. Orbital metastasis in HCC is rare. Prognosis is somber in such cases. The treatment should focus on providing palliation from symptoms.

Keywords

hepatocellular carcinoma - metastasis - orbital - palliation - radiotherapy


Publication History

Article published online:
10 December 2021

© 2021. Indian Society of Medical and Paediatric Oncology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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