Osteologie 2021; 30(04): 340
DOI: 10.1055/s-0041-1736727
Abstract

Magnesium phosphate granules support bone regeneration in a large animal model

L Schröter
1   Institute of Orthopedic Research and Biomechanics, Ulm University Medical Center, Germany
,
F Kaiser
2   Department for Functional Materials in Medicine and Dentistry, University of Würzburg, Germany
,
S Stein
1   Institute of Orthopedic Research and Biomechanics, Ulm University Medical Center, Germany
,
B T Krüger
1   Institute of Orthopedic Research and Biomechanics, Ulm University Medical Center, Germany
,
U Gbureck
2   Department for Functional Materials in Medicine and Dentistry, University of Würzburg, Germany
,
A Ignatius
2   Department for Functional Materials in Medicine and Dentistry, University of Würzburg, Germany
› Author Affiliations
› Further Information
 

Introduction

Magnesium phosphate (MgP) minerals have comparable characteristics to calcium phosphate-based bone substitutes, but degrade more rapidly under physiological conditions [1] [2] [3]. The current study aimed to evaluate the bone regeneration capacity of MgP granules in a mechanically unloaded, critical-size defect model in the trabecular bone of sheep.



Publication History

Article published online:
04 November 2021

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  • References

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  • 2 Ostrowski et al. ACS Biomaterials Science & Engineering 2016. 2(7) 1067–1083
  • 3 Nabiyouni et al. Acta Biomater 2018. 66 (2018) 23–43