3D tissue engineering with a novel bioreactor

Introduction

3D cultivation provides a more realistic model of human tissue in comparison to traditional 2D cultivation [1] [2]. Various 3D cell culture systems have been developed so far to study the three dimensional interaction between cells and the extracellular matrix surrounding them and to later create artificial tissues [3] [4]. 3D culture techniques with the possibility of constant supply of fresh nutrients are essential, but not yet broadly established.

Publication History

Article published online:
04 November 2021

• References

• 1 Page et al. Cell Tissue Res 2013. 352, 123–131
• 2 Gupta et al. Bioeng Transl Med 2016. 1, 63–81
• 3 Baker et al. J Cell Sci 2012. 125, 3015–3024
• 4 Jensen et al. Acta Pharm Sin 2018. B 8, 756–766