Osteologie 2021; 30(04): 341-342
DOI: 10.1055/s-0041-1736731
Abstract

Assessment of bone matrix composition in teleost fish and humans using Raman spectroscopy

B Yazigi
1   Department of Osteology and Biomechanics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
,
F N Schmidt
1   Department of Osteology and Biomechanics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
,
IAK Fiedler
1   Department of Osteology and Biomechanics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
,
B Busse
1   Department of Osteology and Biomechanics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
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Introduction

Bony fish (i.e. teleosts) are emerging small-sized animal models to investigate bone quality, metabolism, and disease pathomechanisms. In particular, species as the swordfish (Xiphias gladius) [1] and killifish (Nothobranchius furzeri) [2] have been recently introduced to the musculoskeletal disciplines because of their peculiar hard tissue biology. We carried out a comprehensive ex vivo analysis of bone tissue to compare the hard tissue properties of the swordfish rostrum, and the killifish vertebral bone with human bone tissue. This macromolecular study of the tissue composition reveals species-dependent similarities and differences in tissue composition.



Publikationsverlauf

Artikel online veröffentlicht:
04. November 2021

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