Neuropediatrics 2021; 52(S 01): S1-S53
DOI: 10.1055/s-0041-1739577
Poster Abstracts

New Diagnoses of Children with Multiple Sclerosis in the Years 2015–2019 in North Rhine-Westphalia with the Help of the Patient Registry for Children with Multiple Sclerosis

A. Kyprianou
1   Vestische Kinder- und Jugendklinik Datteln, Universitätz Witten/Herdecke, DE, Germany
,
T. Deba
2   Klinik für Kinder- und Jugendmedizin, Universitätsklinikum Münster, DE, Germany
,
M. Karenfort
3   Klinik für Allgemeine Pädiatrie, Neonatologie und Kinderkardiologie, Universitätsklinikum Düsseldorf, DE, Germany
,
C. Thiels
4   Kinder- und Jugendmedizin, Universitätsklinikum der Ruhr- Universität Bochum, DE, Germany
,
M. Häusler
5   Klinik für Kinder- und Jugendmedizin, Uniklinik RWTH Aachen, DE, Germany
,
N. Rademacher
6   Klinik für Kinderheilkunde I, Universitätsklinikum Essen, DE, Germany
,
U. Mause
7   Klinik für Kinder- und Jugendmedizin, Klinikum Dortmund, DE, Germany
,
A. Koy
8   Kinderklinik, Uniklinik Köln, DE, Germany
,
S. Lutz
9   Helios Klinikum Niederberg, DE, Germany
,
P. Vaassen
10   Klinik für Kinder- und Jugendmedizin, Sana Kliniken Duisburg, DE, Germany
,
F. Ebinger
11   Klinik für Kinder- und Jugendmedizin, St. Vincenz- Krankenhaus Paderborn, DE, Germany
,
G. Classen
12   Klinik für Kinder- und Jugendmedizin, Evangelisches Klinikum Bethel, DE, Germany
,
B. Erdlenbruch
13   Klinik für Kinder- und Jugendmedizin, Johannes Wesling Klinikum Minden, DE, Germany
,
J. Schlump
14   Klinik für Kinder- und Jugendmedizin, Gemeinschaftskrankenhaus Herdecke, DE, Germany
,
M. Pritsch
15   DRK Kinderklinik Siegen, DE, Germany
,
J. Kreth
16   Klinik für Kinder und Jugendliche, Klinikum Leverkusen, DE, Germany
,
A. Flechtenmacher
17   Klinik für Kinder und Jugendliche, Lukaskrankenhaus Neuss, DE, Germany
,
A. Stahmann
18   MS Forschungs- und Projektentwicklungs- gGmbH, DE, Germany
,
K. Rostásy
1   Vestische Kinder- und Jugendklinik Datteln, Universitätz Witten/Herdecke, DE, Germany
› Author Affiliations
› Further Information
 

Background/Purpose: Multiple sclerosis (MS) is the most common permanent neurological disability among young adults. In 2 to 5% of the cases, the disease onset occurs before the age of 16 years. In North Rhine-Westphalia (NRW), there are no precise data regarding pediatric MS.

The aim of this project is in collaboration with all the centers treating children with MS in NRW to identify the prevalence in the last 5 years. Moreover, it is intended to record the new cases and their clinical course over the next 4 years. The project was sponsored by the DMSG.

Methods: Seventeen centers in NRW have agreed to collaborate with the NRW pediatric patient registry for MS. In a first project, the facilities were asked to record new cases of pediatric MS from 2015 to 2019 according to the McDonald criteria from 2013 or 2017. Birthdate, date of diagnosis, and gender were recorded. Statistics were carried out using SPSS.

Results: Between the years 2015 and 2019, a total of 167 children in NRW were diagnosed with multiple sclerosis. The patients had a median age at onset of 14.5 (range: 5–17), 119 (71.3%) were female, and 48 (28.7%) were male. We calculated among the underage population of NRW an incidence rate between 0.88 (2015) and 1.33 (2019) per 100,000 people.

Conclusion: Pediatric MS appears to be much more frequent as previously estimated. Many questions regarding clinical course, drug acceptance, and compatibility, as well as the social aspects of the disease in a young age still have to be answered.



Publication History

Article published online:
28 October 2021

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