Acute Cytomegalovirus (CMV) Hepatitis in an Immunocompetent Female, A Case Report and Review of Literature

Cytomegalovirus (CMV) is a common pathogen with a worldwide seroprevalence ranging from 40-100%. Hepatic involvement varies depending on the patient’s immune condition with severe disease being usually encountered in immunocompromised patients. On the other hand, most cases among immunocompetent subjects are asymptomatic and CMV hepatitis requiring hospitalization is very rare. Thus, it’s not uncommon for such diagnosis to be delayed, especially among immunocompetent patients, leading to an extensive and unnecessary diagnostic workup. This case report describes a 26-year-old immunocompetent female with an acute CMV hepatitis presenting with a one-week history of headache and nausea. The CMV-Infection was diagnosed based on positive serology and polymerase chain reaction (PCR). The patient was treated conservatively with documented spontaneous viral elimination and consequent clinical improvement and normalization of liver enzymes.

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Artikel online veröffentlicht:
26. Januar 2022