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CC BY-NC-ND 4.0 · J Neurol Surg Rep 2022; 83(01): e13-e18
DOI: 10.1055/s-0041-1741069
Original Article

Squamous Cell Carcinoma of the Temporal Bone Arising from Cholesteatoma: A Case Report and Review of the Literature

Juan C. Yanez-Siller
1   Department of Otolaryngology-Head and Neck Surgery, University of Missouri, Columbia, Missouri, United States
,
Carissa Wentland
1   Department of Otolaryngology-Head and Neck Surgery, University of Missouri, Columbia, Missouri, United States
,
Kelly Bowers
2   Department of Pathology and Anatomical Sciences, University of Missouri, Columbia, Missouri, United States
,
N. Scott Litofsky
3   Division of Neurosurgery, Department of Surgery, University of Missouri, Columbia, Missouri, United States
,
Arnaldo L. Rivera
1   Department of Otolaryngology-Head and Neck Surgery, University of Missouri, Columbia, Missouri, United States
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Abstract

Objective Present a case of squamous cell carcinoma of the temporal bone (SCCTB) arising in a 61-year-old female with a prior history of cholesteatoma and persistent otologic symptoms and review the current literature regarding this disease presentation.

Setting Tertiary academic center.

Patient A 61-year-old female with a history of left ear cholesteatoma for which she had undergone surgery 54 years prior. The patient presented with a persistent history of otorrhea since first surgery and developed exacerbation of symptoms just prior to presentation at our department. The clinical picture was highly suspicious of cholesteatoma recurrence. However, the biopsy was consistent with squamous cell carcinoma.

Intervention Surgical debulking of the lesion was followed by a brief course of radiation therapy later halted by the patient due to side effect intolerance.

Conclusion SCCTB may arise from cholesteatoma. A high index of suspicion for SCCTB should be maintained in patients with a prior history of cholesteatoma and evidence of a temporal bone mass with persistent otologic symptoms.

Keywords

squamous cell carcinoma of temporal bone - cholesteatoma - skull base - chronic otorrhea

Note

Portions of this work were presented as a poster presentation at the 30th Annual North American Skull Base Society Meeting, San Antonio, Texas, February 7–9, 2020.


Disclosure

The authors have no personal, financial, or institutional interest to declare.




Publication History

Received: 04 October 2020

Accepted: 14 April 2021

Article published online:
08 February 2022

© 2022. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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