Semin Neurol 2022; 42(01): 048-059
DOI: 10.1055/s-0041-1741495
Review Article

Digital Phenotyping in Clinical Neurology

1   Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts
› Author Affiliations


Internet-connected devices, including personal computers, smartphones, smartwatches, and voice assistants, have evolved into powerful multisensor technologies that billions of people interact with daily to connect with friends and colleagues, access and share information, purchase goods, play games, and navigate their environment. Digital phenotyping taps into the data streams captured by these devices to characterize and understand health and disease. The purpose of this article is to summarize opportunities for digital phenotyping in neurology, review studies using everyday technologies to obtain motor and cognitive information, and provide a perspective on how neurologists can embrace and accelerate progress in this emerging field.

Publication History

Article published online:
11 January 2022

© 2022. Thieme. All rights reserved.

Thieme Medical Publishers, Inc.
333 Seventh Avenue, 18th Floor, New York, NY 10001, USA