Zentralblatt für Chirurgie - Zeitschrift für Allgemeine, Viszeral-, Thorax- und Gefäßchirurgie, Inhaltsverzeichnis Zentralbl Chir 2017; 142(01): 127-139DOI: 10.1055/s-0042-112683 CME-Fortbildung Georg Thieme Verlag KG Stuttgart · New YorkAngeborene pulmonale MalformationenCongenital Lung MalformationsAutor*innen Hans-Joachim Kirschner Jörg Fuchs Artikel empfehlen Abstract Artikel einzeln kaufen(opens in new window) Der Beitrag stellt Ursachen, Verlauf, diagnostische und therapeutische Möglichkeiten anhand der bronchogenen Zyste, der bronchopulmonalen Sequestration, des kongenitalen lobären Emphysems und der Congenital pulmonary Airway Malformation (CPAM) dar. Die angeborenen pulmonalen Malformationen sind zwar selten, bergen aber ein erhebliches Risiko für respiratorische Probleme beim Neugeborenen, für Infektionen und maligne Transformation im Verlauf. Volltext Referenzen Literatur 1 Herriges M, Morrisey EE. Lung development: orchestrating the generation and regeneration of a complex organ. Development 2014; 141: 502-513 2 Warburton D, El-Hashash A, Carraro G. et al. Lung organogenesis. Curr Top Dev Biol 2010; 90: 73-158 3 Kirmani B, Kirmani B, Sogliani F. Should asymptomatic bronchogenic cysts in adults be treated conservatively or with surgery?. Interact Cardiovasc Thorac Surg 2010; 11: 649-659 4 Rodgers BM, Harman PK, Johnson AM. Bronchopulmonary foregut malformations. The spectrum of anomalies. Ann Surg 1986; 203: 517-524 5 Berrocal T, Madrid C, Novo S. et al. Congenital anomalies of the tracheobronchial tree, lung, and mediastinum: embryology, radiology, and pathology. Radiographics 2004; 24: e17 6 Stiger KB, Woodring JH, Kanga JF. The clinical and imaging spectrum of findings in patients with congenital lobar emphysema. Pediatr Pulmonol 1992; 14: 160-170 7 Laberge JM, Puligandla P, Flageole H. Asymptomatic congenital lung malformations. Semin Pediatr Surg 2005; 14: 16-33 8 Sarper A, Ayten A, Golbasi I. et al. Bronchogenic cyst. Tex Heart Inst J 2003; 30: 105-108 9 Liechty KW, Flake AW. Pulmonary vascular malformations. Sem Ped Surg 2008; 17: 9-16 10 Langston C. New concepts in the pathology of congenital lung malformations. Semin Pediatr Surg 2003; 12: 17-37 11 Holder PD, Langston C. Intralobar pulmonary sequestration (a nonentity?). Pediatr Pulmonol 1986; 2: 147-153 12 Desjardins CP, Khan JG. Pulmonary sequestration. J Pediatr Surg 1987; 22: 750-753 13 Mendeloff EN. Sequestrations, congenital cystic adenomatoid malformations, and congenital lobar emphysema. Semin Thorac Cardiovasc Surg 2004; 16: 209-214 14 Morad NA, al-Malki T, e-Tahir M. Intra-abdominal pulmonary sequestration: diagnostic difficulties. Pathology 1997; 29: 218-220 15 Corbett HJ, Humphrey GM. Pulmonary sequestration. Paediatr Respir Rev 2004; 5: 59-68 16 Belchis D, Cowan M, Mortman K. et al. Adenocarcinoma arising in an extralobar sequestration: a case report and review of the literature. Lung Cancer 2014; 84: 92-95 17 Kravitz RM. Congenital malformations of the lung. Pediatr Clin North Am 1994; 41: 453-472 18 Stocker JT, Madewell JE, Drake RM. Congenital cystic adenomatoid malformation of the lung. Classification and morphologic spectrum. Hum Pathol 1977; 8: 155-171 19 Stocker JT. Congenital pulmonary airway malformation – a new name for and an expanded classification of congenital cystic adenomatoid malformation of the lung. Histopathology 2002; 41: 424-430 20 Shanti CM, Klein MD. Cystic lung disease. Semin Pediatr Surg 2008; 17: 2-8 21 Mann S, Wilson RD, Bebbington MW. et al. Antenatal diagnosis and management of congenital cystic adenomatoid malformation. Semin Fetal Neonatal Med 2007; 12: 477-481 22 Adzick NS, Harrison MR, Glick PL. Fetal cystic adenomatoid malformation: prenatal diagnosis and natural history. J Pediatr Surg 1985; 20: 483-488 23 Thakral CL, Maji DC, Sajwani MJ. Congenital lobar emphysema: experience with 21 cases. Pediatr Surg Int 2001; 17: 88-91 24 Hulnick DH, Naidich DP, McCauley DI. et al. Late presentation of congenital cystic adenomatoid malformation of the lung. Radiology 1984; 151: 569-573 25 Landing BH, Dixon LG. Congenital malformations and genetic disorders of the respiratory tract (larynx, trachea, bronchi, and lungs). Am Rev Respir Dis 1979; 120: 151-185 26 Azizkhan RG, Crombleholme TM. Congenital cystic lung disease: contemporary antenatal and postnatal management. Pediatr Surg Int 2008; 24: 643-657 27 Paksoy N, Demircan A, Altiner M. et al. Localised fibrous mesothelioma arising in an intralobar pulmonary sequestration. Thorax 1992; 47: 837-838 28 Gatzinsky P, Olling S. A case of carcinoma in intralobar pulmonary sequestration. Thorac Cardiovasc Surg 1988; 36: 290-291 29 Nasr A, Himidan S, Pastor AC. et al. Is congenital cystic adenomatoid malformation a premalignant lesion for pleuropulmonary blastoma?. J Pediatr Surg 2010; 45: 1086-1089 30 Federici S, Domenichelli V, Tani G. Pleuropulmonary blastoma in congenital cystic adenomatoid malformation: report of a case. Eur J Pediatr Surg 2001; 11: 196-199 31 Benjamin DR, Cahill JL. Bronchioloalveolar carcinoma of the lung and congenital cystic adenomatoid malformation. Am J Clin Pathol 1991; 95: 889-892 32 Hancock BJ, Di Lorenzo M, Youssef S. Childhood primary pulmonary neoplasms. J Pediatr Surg 1993; 29: 1133-1136 33 Pai S, Eng HL, Lee SY. et al. Rhabdomyosarcoma arising within congenital cystic adenomatoid malformation. Pediatr Blood Cancer 2005; 45: 841-845 34 Lecomte B, Hadden H, Coste K. et al. Hyperechoic congenital lung lesions in a non-selected population: from prenatal detection till perinatal management. Prenat Diagn 2009; 29: 1222-1230 35 Kumar AN. Perinatal management of common neonatal thoracic lesions. Indian J Pediatr 2008; 75: 931-937 36 Conran RM, Stocker JT. Extralobar sequestration with frequently associated congenital cystic adenomatoid malformation, type 2: report of 50 cases. Pediatr Dev Pathol 1999; 2: 454-463 37 Gajewska-Knapik K, Impey L. Congenital lung lesions: Prenatal diagnosis and intervention. Semin Pediatr Surg 2015; 24: 156-159 38 Lee EY, Tracy DA, Mahmood SA. et al. Preoperative MDCT evaluation of congenital lung anomalies in children: comparison of axial, multiplanar, and 3D images. AJR Am J Roentgenol 2011; 196: 1040-1046 39 Nakagawa M, Ozawa Y, Sakurai K. et al. Image quality at low tube voltage (70 kV) and sinogram-affirmed iterative reconstruction for computed tomography in infants with congenital heart disease. Pediatr Radiol 2015; 45: 1472-1479 40 Odev K, Aribas BK, Nayman A. et al. Imaging of cystic and cyst-like lesions of the mediastinum with pathologic correlation. J Clin Imaging Sci 2012; 2: 33 41 Curran PF, Jelin EB, Rand L. et al. Prenatal steroids for microcystic congenital cystic adenomatoid malformations. J Pediatr Surg 2010; 45: 145-150 42 Oepkes D, Devlieger R, Lopriore E. et al. Successful ultrasound-guided laser treatment of fetal hydrops caused by pulmonary sequestration. Ultrasound Obstet Gynecol 2007; 29: 457-459 43 Moldenhauer JS. Ex utero intrapartum therapy. Semin Pediatr Surg 2013; 22: 44-49 44 Singh S, Davenport M. The argument for operative approach to asymptomatic lung lesions. Semin Pediatr Surg 2015; 24: 187-195 45 Patel SR, Meeker DP, Biscotti CV. et al. Presentation and management of bronchogenic cysts in the adult. Chest 1994; 106: 79-85 46 Stanton M, Njere I, Ade-Ajay N. et al. Systematic review and meta-analysis of the postnatal management of congenital cystic lung lesions. J Pediatr Surg 2009; 44: 1027-1033 47 Özcelik U, Göcmen A, Kiper N. et al. Congenital lobar emphysema: evaluation and long-term follow-up of thirty cases at a single center. Pediatr Pulmonol 2003; 35: 384-391 48 Mei-Zahav M, Konen O, Manson D. et al. Is congenital lobar emphysema a surgical disease?. J Pediatr Surg 2006; 41: 1058-1061 49 Muller CO, Berrebi D, Kheniche A. Is radical lobectomy required in congenital cystic adenomatoid malformation?. J Pediatr Surg 2012; 47: 642-645 50 García-Peña P, Lucaya J, Hendry GM. et al. Spontaneous involution of pulmonary sequestration in children: a report of two cases and review of the literature. Pediatr Radiol 1998; 28: 266-270 51 Churg AM, Myers JL. eds. Thurlbeckʼs Pathology of the Lung. 3rd ed.. Stuttgart: Thieme; 2005 52 Nakajima C, Kijimoto C, Yokoyama Y. et al. Longitudinal follow-up of pulmonary function after lobectomy in childhood – factors affecting lung growth. Pediatr Surg Int 1998; 13: 341-345 53 Fuchs J, Kirschner HJ, Warmann SW. et al. Die thorakoskopische anatomiegerechte Lungenresektion im Kindesalter. Zentralbl Chir 2007; 132: 247-250 54 Kirschner HJ, Fuchs J. Erfahrungen mit der minimalinvasiven anatomischen Lungenresektion im Kindesalter. Chir Praxis 2016; 81: 233-242 55 Lieber J, Urla C, Baden W. et al. Experiences and challenges of thoracoscopic lung surgery in the pediatric age group. Int J Surg 2015; 23: 169-175 56 Rothenberg SS. Thoracoscopic pulmonary surgery. Semin Pediatr Surg 2007; 16: 231-237