SGLT2-Hemmung und Reduktion kardiovaskulärer Ereignisse bei Diabetes
29 September 2016 (online)
SGLT2-inhibitors are a novel class of antidiabetic drugs that increase urinary glucose excretion thus lowering blood glucose levels. In addition to their glucose-lowering properties, these agents reduce weight and blood pressure and seem to exhibit additional beneficial effect in the cardiovascular system. The recently published EMPA-REG OUTCOME study demonstrated a reduction in cardiovascular mortality, overall mortality as well as hospitalisation for heart failure by the SGLT2-inhibitor empagliflozin in a population of patients with type 2 diabetes and high cardiovascular risk.
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