Zeitschrift für Orthomolekulare Medizin 2016; 14(04): 5-15
DOI: 10.1055/s-0042-122819
Wissen
Hippokrates Verlag in MVS Medizinverlage Stuttgart GmbH & Co. KG Stuttgart – New York

Entgiftung: Effektiv bei vielen Krankheiten

Joachim Mutter
Further Information

Publication History

Publication Date:
14 July 2017 (online)

Summary

Natürliche und auch künstliche Chemikalien können den Organismus schwächen und krank machen. Für viele Menschen, besonders bei bestehenden Krankheiten oder Beschwerden, kann eine regelmäßige Entgiftung sinnvoll sein. Gegen Metalle, Halbmetalle und manche radioaktive Isotope sind spezifische Gegenmittel (Antidote) verfügbar. Bei anderen Giftstoffen gibt es, außer bei einigen in der Akuttoxikologie (wie z. B. Antiseren gegenüber Schlangengiften, Atropin gegen Cholinesterasehemmstoffen) keine spezifischen Gegenmittel.

Der Autor gibt einen Überblick über die wichtigsten Entgiftungsstrategien bei chronischen Beschwerden sowie praktische Hinweise.

 
  • Literatur

  • 1 Adams JB, Baral M, Geis E. et al. Safety and efficacy of oral DMSA therapy for children with autism spectrum disorders: part B - behavioral results. BMC Clin Pharmacol 2009; 9: 17
  • 2 Alexandrov PN, Kruck TP, Lukiw WJ. Nanomolar aluminum induces expression of the inflammatory systemic biomarker C-reactive protein (CRP) in human brain microvessel endothelial cells (hBMECs). J Inorg Biochem 2015; 152: 210-213
  • 3 Bartova J, Prochazkova J, Kratka Z. et al. Dental amalgam as one of the risk factors in autoimmune diseases. Neuroendocrinol Lett 2003; 24: 65-67
  • 4 Bernard S, Enayati A, Roger H. et al. The role of mercury in the pathogenesis of autism. Mol Psychiatry 2002; 7 Suppl 2 S42-S43
  • 5 BMBF 1995 Forschungserfolg: Erstmals Hinweise über Entstehung von Autoimmunkrankheiten. Forschungsinfo 7.8.1995, Nr 24/25. Bundesministerium für Bildung, Wissenschaft, Forschung und Technologie (BMBF);
  • 6 Böse-O'Reilly S, Drasch G, Beinhoff C. et al. The Mt. Diwata study on the Philippines 2000-treatment of mercury intoxicated inhabitants of a gold mining area with DMPS (2,3-dimercapto-1-propane-sulfonic acid, Dimaval). Sci Total Environ 2003; 307 1–3 71-82
  • 7 Clarke D, Buchanan R, Gupta N. et al. Amelioration of Acute Mercury Toxicity by a Novel, Non-Toxic Lipid Soluble Chelator N,N‘bis-(2-mercaptoethyl)isophthalamide: Effect on Animal Survival, Health, Mercury Excretion and Organ Accumulation. Toxicol Environ Chem 2012; 94 (03) 616-640
  • 8 Crapper McLachlan DR, Dalton AJ, Kruck TP. et al. Intramuscular desferrioxamine in patients with Alzheimer‘s disease. Lancet 1991; 337 8753 1304-1308
  • 9 Daschner F, Mutter J. Sondervotum zu „Amalgam: Stellungnahme aus umweltmedizinischer Sicht“, Mitteilung der Kommission „Methoden und Qualitätssicherung in der Umweltmedizin“ des Robert-Koch-Institutes, Berlin. Bundesgesundheitsbl- Gesundheitsforsch- Gesundheitsschutz 2007; 50: 1432-1433
  • 10 Dorea JG. Exposure to mercury and aluminum in early life: developmental vulnerability as a modifying factor in neurologic and immunologic effects. Int J Environ Res Public Health 2015; 12 (02) 1295-1313
  • 11 Drasch G, Bose-O'Reilly S, Beinhoff C. et al. The Mt. Diwata study on the Philippines 1999--assessing mercury intoxication of the population by small scale gold mining. Sci Total Environ 2001; 267: 151-168
  • 12 Drasch G, Bose-O'Reilly S, Maydl S. et al. Scientific comment on the German human biological monitoring values (HBM values) for mercury. Int J Hyg Environ Health 2002; 205: 509-512
  • 13 Drasch G, Mail der S, Schlosser C. et al. Content of non-mercury-associated selenium in human tissues. Biol Trace Elem Res 2000; 77: 219-230
  • 14 Drasch G, Wanghofer E, Roider G. Are blood, urine, hair, and muscle valid bio-monitoring parameters for the internal burden of men with the heavy metals mercury, lead and cadmium?. Trace Elem Electrolytes 1997; 14: 116-123
  • 15 Drevnick PE, Lamborg CH, Horgan MJ. Increase in mercury in Pacific yellowfin tuna. Environ Toxicol Chem 2015; 34 (04) 931-934
  • 16 Duhr EF, Pendergrass JC, Slevin JT. et al. HgEDTA complex inhibits GTP interactions with the E-site of brain beta-tubulin. Toxicol Appl Pharmacol 1993; 122: 273-280
  • 17 Ericson JE, Shirahata H, Patterson CC. Skeletal concentrations of lead in ancient Peruvians. N Engl J Med 1979; 300 (17) 946-951
  • 18 Ferrero ME. Rationale for the Successful Management of EDTA Chelation Therapy in Human Burden by Toxic Metals. Biomed Res Int 2016; 2016: 8274504
  • 19 Frustaci A, Magnavita N, Chimenti C. et al. Marked elevation of myocardial trace elements in idiopathic dilated cardiomyopathy compared with secondary cardiac dysfunction. J Am Coll Cardiol 1999; 33 (06) 1578-1583
  • 20 Hahn LJ, Kloiber R, Leininger RW. et al. Whole-body imaging of the distribution of mercury released from dental fillings into monkey tissues. FASEB J 1990; 4: 3256-3260
  • 21 Hahn LJ, Kloiber R, Vimy MJ. et al. Dental „silver“ tooth fillings: a source of mercury exposure revealed by whole-body image scan and tissue analysis. FASEB J 1989; 3: 2641-2646
  • 22 Haley BE. Mercury toxicity: Genetic susceptibility and synergistic effects. Medical Veritas 2005; 2: 535-542 www.1796kotok.com/pdfs/haley.pdf
  • 23 Haley Boyd. Universität Kentucky; Vortrag 12.6.2010 München: Slide 9 http://www.draloisdengg.at/bilder/pdf/BoydHaleyToxicity_Oral_Infection_Amalgam.pdf
  • 24 Harris HH, Vogt S, Eastgate H. et al. Migration of mercury from dental amalgam through human teeth. J Synchrotron Radiat 2008; 15 Pt 2 123-128
  • 25 Holmes AS, Blaxill MF, Haley BE. Reduced levels of mercury in first baby haircuts of autistic children. Int J Toxicol 2003; 22: 277-285
  • 26 Hultman P, Johansson U, Turley SJ. et al. Adverse immunological effects and autoimmunity induced by dental amalgam and alloy in mice. FASEB J 1994; 8: 1183-1190
  • 27 Kennedy R. Thimerosal and autism: Lets the science speak. Skyhorse Publishing; 2014
  • 28 Kim YN, Kim YA, Yang AR. et al. Relationship between Blood Mercury Level and Risk of Cardiovascular Diseases: Results from the Fourth Korea National Health and Nutrition Examination Survey (KNHANES IV) 2008-2009. Prev Nutr Food Sci 2014; 19 (04) 333-342
  • 29 Klinghardt D. Schwermetalle und ihre Wirkungen auf die Gesundheit. Vortrag auf Schloß Elmau; 1996. www.rohkostwiki.de/wiki/Vortrag_von_Dr._med._Dietrich_Klinghardt_%C3%BCber_Schwermetalle
  • 30 Leitzmann C, Mutter J. Vitamin B12 Kontroverse. Wurzel 2014; 1: 38-44 http://www.detoxklinik.de/files/9813/9927/9204/B12_Kontroverse_comp.pdf
  • 31 Leong CC, Syed NI, Lorscheider FL. Retrograde degeneration of neurite membrane structural integrity of nerve growth cones following in vitro exposure to mercury. Neuroreport 2001; 12: 733-737
  • 32 Lettmeier B, Böse o Reilly S, Drasch G. Proposal for a revised reference concentration (RfC) for mercury vapour in adults. Sci Total Environ 2010; 408 (17) 3530-3535
  • 33 Lorscheider FL, Vimy MJ, Summers AO. Mercury exposure from „silver“ tooth fillings: emerging evidence questions a traditional dental paradigm. FASEB J 1995; 9: 504-508
  • 34 Mangelsdorf I. Healing Motorneurondiseas – a case report [Master Thesis]. Europa Universität Frankfurt (Oder): 2016
  • 35 Menke A, Muntner P, Batuman V. et al. Blood lead below 0.48 micromol/L (10 microg/dL) and mortality among US adults. Circulation 2006; 114 (13) 1388-1394
  • 36 Mutter J, Naumann J, Walach H. et al. Amalgam: Eine Risikobewertung unter Berücksichtigung der neuen Literatur bis 2005. Gesundheitswesen 2005a 67: 204-216
  • 37 Mutter J, Naumann J, Walach H. et al. Mercury and autism: Accelerating Evidence?. Neuroendocrin Lett 2005b 26: 439-446
  • 38 Mutter J. Is Dental Amalgam Safe for Humans?. The European Commission‘s SCENIHR Opinion. J Occup Med Toxicol 2011; 6: 2
  • 39 Mutter J. Amalgam-Risiko für die Menschheit. Weil der Stadt; Natura viva: 2000
  • 40 Mutter J. Gesund statt chronisch krank. Weil der Stadt; Natura viva: 2009
  • 41 Mutter J. Lass Dich nicht vergiften. München: Gräfe & Unzer; 2012
  • 42 National Institute of Health 2015: Pilot Proof of Concept Study of NBMI Treatment of Mercury Intoxication (NBMI) https://clinicaltrials.gov/ct2/show/NCT02486289
  • 43 Omura Y, Beckman SL. Role of mercury (Hg) in resistant infections & effective treatment of Chlamydia trachomatis and Herpes family viral infections (and potential treatment for cancer) by removing localized Hg deposits with Chinese parsley and delivering effective antibiotics using various drug uptake enhancement methods. Acupunct Electrother Res 1995; 20 3–4 195-229
  • 44 Opitz H, Schweinsberg F, Grossmann T. et al. Demonstration of mercury in the human brain and other organs 17 years after metallic mercury exposure. Clin Neuropathol 1996; 15: 139-144
  • 45 Panahi Y, Darvishi B, Jowzi N. et al. Chlorella vulgaris: A Multifunctional Dietary Supplement with Diverse Medicinal Properties. Curr Pharm Des 2016; 22 (02) 164-173
  • 46 Patterson C, Ericson J, Manea-Krichten M. et al. Natural skeletal levels of lead in Homo sapiens sapiens uncontaminated by technological lead. Sci Total Environ 1991; 107: 205-236
  • 47 Percy ME, Kruck TP, Pogue AI. et al. Towards the prevention of potential aluminum toxic effects and an effective treatment for Alzheimer‘s disease. J Inorg Biochem 2011; 105 (11) 1505-1512
  • 48 Rogan WJ, Ware JH. Exposure to lead in children – how low is low enough?. N Engl J Med 2003; 348: 1515-1516
  • 49 Rooney JP. The retention time of inorganic mercury in the brain – a systematic review of the evidence. Toxicol Appl Pharmacol 2014; 274 (03) 425-435
  • 50 Ruprecht J. Dimaval (DMPS)/ DMPS-Heyl- wissenschaftliche Produktmonographie. 6. Aufl. 2010
  • 51 Schubert J, Riley EJ, Tyler SA.  . Combined effects in toxicology – a rapid systematic testing procedure: cadmium, mercury, and lead. J Toxicol Environ Health 1978; 4: 763-776
  • 52 Singh A1, Singh SP, Bamezai R. Inhibitory potential of Chlorella vulgaris (E-25) on mouse skin papillomagenesis and xenobiotic detoxication system. Anticancer Res 1999; 19 (3A): 1887–1891
  • 53 Somers EC, Ganser MA, Warren JS. et al. Mercury Exposure and Antinuclear Antibodies among Females of Reproductive Age in the United States: NHANES. Environ Health Perspect 2015; 123 (08) 792-798
  • 54 Stejskal J, Stejskal VD. The role of metals in autoimmunity and the link to neuroendocrinology. Neuroendocrinol Lett 1999; 20: 351-364
  • 55 Thier R, Bonacker D, Stoiber T. et al. Interaction of metal salts with cytoskeletal motor protein systems. Toxicol Lett 2003; 140–141: 75-81
  • 56 Uchikawa T, Kumamoto Y, Maruyama I. et al. Enhanced elimination of tissue methylmercury in Parachlorella beijerinckii-fed mice. J Toxicol Sci 2011; 36 (01) 121-126
  • 57 UNEP (United Nations Environment Programm) (Chemicals): Global Mercury Assesment. UNEP Chemicals Geneva; Dezember 2002
  • 58 Virtanen JK, Voutilainen S, Rissanen TH. et al. Mercury, fish oils, and risk of acute coronary events and cardiovascular disease, coronary heart disease, and all-cause mortality in men in eastern Finland. Arterioscler Thromb Vasc Biol 2005; 25 (01) 228-233
  • 59 Walach H, Mutter J, Deth R. Inorganic Mercury and Alzheimer‘s Disease – Results of a Review and a Molecular Mechanism. In: Martin CR, Preedy VR, eds. Diet and Nutrition in Dementia and Cognitive Decline London: Academic Press, Elsevier; 2014: 593-601
  • 60 WHO, ed. Environmental Health Criteria 118: Inorganic mercury. Geneva: 1991
  • 61 Willhite CC, Karyakina NA, Yokel RA. et al. Systematic review of potential health risks posed by pharmaceutical, occupational and consumer exposures to metallic and nanoscale aluminum, aluminum oxides, aluminum hydroxide and its soluble salts. Crit Rev Toxicol 2014; 44 Suppl 4 1-80
  • 62 Yassa HA. Autism: a form of lead and mercury toxicity. Environ Toxicol Pharmacol 2014; 38 (03) 1016-1024