Download PDF
CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2022; 43(02): 189-192
DOI: 10.1055/s-0042-1742443
Grand Round

Ewing Sarcoma of Phalanx—A Common Tumor with an Uncommon Presentation

Suresh Babu MC
1   Department of Medical Oncology, Kidwai Memorial Institute of Oncology, Bengaluru, Karnataka, India
,
Akansha Choudhary
1   Department of Medical Oncology, Kidwai Memorial Institute of Oncology, Bengaluru, Karnataka, India
,
Sreevalli A. 
1   Department of Medical Oncology, Kidwai Memorial Institute of Oncology, Bengaluru, Karnataka, India
,
Linu Abraham Jacob
1   Department of Medical Oncology, Kidwai Memorial Institute of Oncology, Bengaluru, Karnataka, India
,
Lokesh KN 
1   Department of Medical Oncology, Kidwai Memorial Institute of Oncology, Bengaluru, Karnataka, India
,
Rudresha AH
1   Department of Medical Oncology, Kidwai Memorial Institute of Oncology, Bengaluru, Karnataka, India
,
Rajeev LK
1   Department of Medical Oncology, Kidwai Memorial Institute of Oncology, Bengaluru, Karnataka, India
,
Smitha Saldanha
1   Department of Medical Oncology, Kidwai Memorial Institute of Oncology, Bengaluru, Karnataka, India
,
Champaka G.
2   Department of Pathology, Kidwai Memorial Institute of Oncology, Bengaluru, Karnataka, India
› Author Affiliations Funding None.
› Further Information
   Permissions and Reprints

Introduction

Ewing sarcoma (ES) is a small, blue, round cell tumor usually affecting long bones. In 90% of the cases, it occurs in patients aged from 5 to 25 years. While the incidence shows a peak during the second decade of life, it is extremely rare after the third decade of life.[1] [2] The disease shows a slight predilection for males (male to female ratio of 1.6:1.0).[3] It rarely arises in fingers. Here, we present a case of ES of phalanx in an adult.

Source(s) of support

None


Declarations

The authors certify that they have obtained all appropriate patient consent forms. In the form, the patient has given her consent for her images and other clinical information to be reported in the journal. The patient understands that her name and initials will not be published and due efforts will be made to conceal her identity but anonymity cannot be guaranteed.


Competing Interests

None of the authors have any competing interests.


Authors' Contributions

SB and AC contributed to the conception of the study.SV, LAJ, LD, and SS were responsible for the acquisition. SA, LAJ, SBMC, LKN, AHR, and LKR drafted the work. LD, LAJ, and LKR substantively revised it. All authors have read and approved the manuscript.




Publication History

Article published online:
14 March 2022

© 2022. Indian Society of Medical and Paediatric Oncology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India

 

  • References

  • 1 Campanacci M. Bone and soft tissue tumors. Springer-Verlag Wien.; 1999. DOI: 10.1007/978-3-7091-3846-5
    CrossrefGoogle Scholar
  • 2 Mirra J. Bone Tumors: Clinical, Radiologic and Pathologic Correlations. Philadelphia: Lea & Febiger; 1989
    Google Scholar
  • 3 Grünewald TGP, Cidre-Aranaz F, Surdez D. et al. Ewing sarcoma. Nat Rev Dis Primers 2018; 4 (01) 5
    CrossrefPubMedGoogle Scholar
  • 4 Seroussi D, Renauld V, Hébrard W, Duport G, Cohrs D. [Ewing sarcoma of thumb: report of a case and review of the literature]. Ann Chir Plast Esthet 2004; 49 (04) 378-382 [Review. French]
    CrossrefPubMedGoogle Scholar
  • 5 Lin PP, Wang Y, Lozano G. Mesenchymal stem cells and the origin of Ewing's Sarcoma. Sarcoma 2011; 2011: 276463
    PubMedGoogle Scholar
  • 6 Lynch AD, Gani F, Meyer CF, Morris CD, Ahuja N, Johnston FM. Extraskeletal versus skeletal Ewing sarcoma in the adult population: controversies in care. Surg Oncol 2018; 27 (03) 373-379
    CrossrefPubMedGoogle Scholar
  • 7 Jahanseir K, Folpe AL, Graham RP. et al. Ewing sarcoma in older adults: a clinicopathologic study of 50 cases occurring in patients aged 340 years, with emphasis on histologic mimics. Int J Surg Pathol 2020; 28 (04) 352-360
    CrossrefPubMedGoogle Scholar
  • 8 Biswas B, Shukla NK, Deo SVS. et al. Evaluation of outcome and prognostic factors in extraosseous Ewing sarcoma. Pediatr Blood Cancer 2014; 61 (11) 1925-1931
    CrossrefPubMedGoogle Scholar
  • 9 Heidi V, Russell HV, Pappo AS, Nuchtern JG, Kornguth DG, Wang LL. Childhood cancers. Solid tumors of childhood. In: DeVita VT, Lawrence TS, Rosenberg SA. eds. Devita, Hellman & Rosenberg's Cancer: Principles & Practice of Oncology. 8th edition.. Philadelphia: Lippincott Williams & Wilkins; 2008
    Google Scholar
  • 10 Baccari S, Hamdi MF, Mabrouki Z, Daghfous M, Tarhouni L. Ewing's sarcoma of the finger: report of two cases and literature review. Orthop Traumatol Surg Res 2012; 98 (02) 233-237
    CrossrefPubMedGoogle Scholar
  • 11 Fujii H, Honoki K, Kobata Y, Yajima H, Kido A, Takakura Y. Ewing sarcoma of the proximal phalanx: case report. J Plast Surg Hand Surg 2014; 48 (06) 441-443
    CrossrefPubMedGoogle Scholar
  • 12 Chan RC, Sutow WW, Lindberg RD, Samuels ML, Murray JA, Johnston DA. Management and results of localized Ewing's sarcoma. Cancer 1979; 43 (03) 1001-1006
    CrossrefPubMedGoogle Scholar
  • 13 Zucker JM, Henry-Amar M, Sarrazin D, Blache R, Patte C, Schweisguth O. Intensive systemic chemotherapy in localized Ewing's sarcoma in childhood. A historical trial. Cancer 1983; 52 (03) 415-423
    CrossrefPubMedGoogle Scholar
  • 14 Rosen G, Caparros B, Mosende C, McCormick B, Huvos AG, Marcove RC. Curability of Ewing's sarcoma and considerations for future therapeutic trials. Cancer 1978; 41 (03) 888-899
    CrossrefPubMedGoogle Scholar
  • 15 Grier HE, Krailo MD, Tarbell NJ. et al. Addition of ifosfamide and etoposide to standard chemotherapy for Ewing's sarcoma and primitive neuroectodermal tumor of bone. N Engl J Med 2003; 348 (08) 694-701
    CrossrefPubMedGoogle Scholar
  • 16 Womer RB, West DC, Krailo MD. et al. Randomized controlled trial of interval-compressed chemotherapy for the treatment of localized Ewing sarcoma: a report from the Children's Oncology Group. J Clin Oncol 2012; 30 (33) 4148-4154
    CrossrefPubMedGoogle Scholar
  • 17 Wolthuizen R, Nieken J, Overbosch J, Pool SMW. An extraosseous Ewing sarcoma of the index finger masquerading as a benign tumor. J Hand Surg Am 2020 Apr;45:336.e1–366.e4.doi.org/10.1016/j.jhsa.2019.05.009.E pub 2019 Jul 18.PMID: 31327500
    Google Scholar