CC BY-NC-ND 4.0 · Avicenna J Med 2022; 12(01): 031-033
DOI: 10.1055/s-0042-1743209
Case Report

A Case of Minimal Change Disease after SARS-CoV-2 Vaccination under the Age of 18

Mohamad Nour Alhosaini
1   Department of Nephrology, American Hospital, Dubai, United Arab Emirates
› Author Affiliations


This is a care report of a 16-year-old-male who developed de novo minimal change disease following the second dose of the Pfizer vaccine. The patient developed sudden onset edema and 10 kg weight gain. He had nephrotic range proteinuria with normal renal function. Kidney biopsy with adequate sample confirmed minimal change disease. The patient improved after 1 week of starting prednisone. This is the first case of minimal change disease after the Pfizer vaccine in the teenager population since expanding the age groups to allow younger subjects to receive the vaccine. Reporting cases at different age groups will help in trying to clarify whether the increasing reports of nephrotic syndrome following the vaccination are accidental or cause–effect relationship.

Publication History

Article published online:
10 March 2022

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