Download PDF
CC BY-NC-ND 4.0 · World J Nucl Med 2022; 21(01): 059-061
DOI: 10.1055/s-0042-1744199
Case Report

Renal Spindle Cell Tumor with Thrombus Extension into the Inferior Vena Cava and the Right Atrium Depicted by PET/CT Scan

Deya' Aldeen Sweedat
1   Department of Nuclear Medicine, King Hussein Cancer Center, Amman, Jordan
,
Nabeela Al-Hajaj
1   Department of Nuclear Medicine, King Hussein Cancer Center, Amman, Jordan
,
Jakub Khzouz
2   Department of Histopathology, King Hussein Cancer Center, Amman, Jordan
,
Akram Al-Ibraheem
1   Department of Nuclear Medicine, King Hussein Cancer Center, Amman, Jordan
› Author Affiliations
› Further Information
   Permissions and Reprints

Abstract

Tumor thrombus (also called intravascular tumor extension) can be defined as tumor extending into vessel; typically a vein, it occurs in a lot of malignancies like hepatocellular carcinoma, Wilms tumor, and others.[1] Tumor thrombus has been reported to demonstrate increase in fluorine-18 fluorodeoxyglucose (FDG) uptake that would differentiate it from the benign bland thrombus which would not take up FDG on positron emission tomography/computed tomography (PET/CT) scan.[1] We present a case of spindle cell sarcoma of right kidney whose baseline contrast-enhanced CT revealed a mass replacing the right kidney and right renal vein associated with thrombus in the inferior vena cava (IVC). 18F-FDG PET/CT imaging was done that revealed an FDG-avid hypermetabolic malignant right renal mass with hypermetabolic IVC thrombus extending to the right atrium.

Keywords

tumor thrombus - PET/CT - spindle cell sarcoma - 18F-FDG


Publication History

Article published online:
24 February 2022

© 2022. World Association of Radiopharmaceutical and Molecular Therapy (WARMTH). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India

 

  • References

  • 1 Abdelfattah A, El Wazir M, Ali YZ, Naser J, Wiley BM. Renal cell carcinoma with thrombus extension into the inferior vena cava and the right atrium: a case report. CASE (Phila) 2020; 4 (04) 274-277
    CrossrefPubMedGoogle Scholar
  • 2 Quencer KB, Friedman T, Sheth R, Oklu R. Tumor thrombus: incidence, imaging, prognosis and treatment. Cardiovasc Diagn Ther 2017; 7 (Suppl. 03) S165-S177
    CrossrefPubMedGoogle Scholar
  • 3 Lai P, Bomanji JB, Mahmood S. et al. Detection of tumour thrombus by 18F-FDG-PET/CT imaging. Eur J Cancer Prev 2007; 16 (01) 90-94
    CrossrefPubMedGoogle Scholar
  • 4 Sharma P, Kumar R, Jeph S. et al. 18F-FDG PET-CT in the diagnosis of tumor thrombus: can it be differentiated from benign thrombus?. Nucl Med Commun 2011; 32 (09) 782-788
    CrossrefPubMedGoogle Scholar
  • 5 Rydberg JN, Sudakoff GS, Hellman RS, See WA. Positron emission tomography-computed tomography imaging characteristics of an inferior vena cava tumor thrombus with magnetic resonance imaging correlation. J Comput Assist Tomogr 2004; 28 (04) 517-519
    CrossrefPubMedGoogle Scholar
  • 6 Bek CS, Kim HW, Won KS, Song BI. Spindle cell sarcoma of the iliac vein on 18 F-FDG PET/CT. Clin Nucl Med 2017; 42 (04) 293-294
    CrossrefPubMedGoogle Scholar
  • 7 Figueroa AJ, Stein JP, Lieskovsky G, Skinner DG. Adrenal cortical carcinoma associated with venous tumour thrombus extension. Br J Urol 1997; 80 (03) 397-400
    CrossrefPubMedGoogle Scholar
  • 8 Nouh MA, Inui M, Kakehi Y. Renal cell carcinoma with IVC thrombi; current concepts and future perspectives. Clin Med Oncol 2008; 2: 247-256
    PubMedGoogle Scholar