CC BY-NC-ND 4.0 · International Journal of Recent Surgical and Medical Sciences 2023; 09(01): 006-011
DOI: 10.1055/s-0042-1745746
Original Article

Effect of Two Different Temperature Settings on Patient Comfort Level during Respiratory Therapy by High-Flow Nasal Cannula

Mamta Kumari
1   Department of Anaesthesia, Operation theater complex 3rd floor, ESIC Medical College, NH-3, Faridabad, India
Rashmi Taneja
1   Department of Anaesthesia, Operation theater complex 3rd floor, ESIC Medical College, NH-3, Faridabad, India
Niharika Grover
1   Department of Anaesthesia, Operation theater complex 3rd floor, ESIC Medical College, NH-3, Faridabad, India
Megha Soni
1   Department of Anaesthesia, Operation theater complex 3rd floor, ESIC Medical College, NH-3, Faridabad, India
› Author Affiliations
Funding This study was funded by the ESIC Medical College, NH-3, Faridabad.


Background Hypoxemic respiratory failure may require high flow O2 therapy (>15 L/m), which can be delivered using a high-flow nasal cannula (HFNC) device. There are three variables: FiO2, flow, and temperature that can be controlled while using HFNC. This study was planned to assess the degree of comfort level of patients at two different temperature settings.

Methods A prospective interventional cross-over study was performed on 40 hypoxemic respiratory failure patients, who were on HFNC. Primary outcome was to assess patient comfort during HFNC therapy at two different temperatures (31 and 37°C), at the flow of 60 L/m for 30 minutes at each temperature setting, leaving FiO2 unchanged. After 30 minutes of each temperature setting, the comfort level was assessed using 11 score visual numerical scale (ranging from 0 to 10) together with other vital parameters.

Result Patients were found to be more comfortable at temperature settings of 31°C than at 37°C (p-value < 0.05%). Also, an increase in blood pressure was observed at 37°C after completion of 30 minutes, which was statistically significant but not clinically significant.

Conclusion Starting HFNC therapy at lower temperature gives better patient acceptance and reduces chances of failure due to discomfort.

Authors' Contributions

Dr. Mamta Kumari– concept, design, literature search.

Dr. Megha Soni- data acquisition, literature search.

Dr. Niharika Grover-literature search, definition of intellectual content, manuscript preparation.

Dr. Rashmi Taneja –manuscript editing and review.

Dr. Mamta Kumari is the guarantor and takes the responsibility for the integrity of work as a whole from inception to published article.


This manuscript has been read and approved by all the authors, requirements for authorship have been met, and each author believes that the manuscript presents the honest work. Article is not published nor under consideration, in part or whole simultaneously in any other journal or any other proceedings.

Publication History

Article published online:
14 April 2022

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