CC BY-NC-ND 4.0 · Journal of Health and Allied Sciences NU 2023; 13(01): 090-097
DOI: 10.1055/s-0042-1749182
Original Article

A Preliminary Survey of the Postacute Symptoms of COVID-19 among Hospital-Discharged Patients and a Proposed Quantitative Framework for Assessment

1   Department of Medical Research and Data Management, Sanjiban Hospital, Fuleswar, Howrah, West Bengal, India
Subhasis Mitra
2   Sanjiban Hospital, Fuleswar, Howrah, West Bengal, India
Dalia Mitra
2   Sanjiban Hospital, Fuleswar, Howrah, West Bengal, India
› Institutsangaben


Background Following a massive outbreak of the coronavirus disease 2019 (COVID-19) pandemic, a significant number of survivors are still suffering from residual symptoms and complications. We designed a preliminary study to evaluate such symptom spectra in COVID-19 patients who had been discharged from the hospital.

Methods A telephone interview was conducted with 100-randomly chosen hospital-discharged COVID-19 survivors from the electronic patient record. The interview structure and method were developed by a panel of experts. A specially trained group conducted the interviews and data collection. The statistical analysis was performed in accordance with the data type (continuous and categorical). Group comparisons were also done between intensive care unit (ICU) versus general ward admission, and patients discharged between 3 and 12 weeks versus more than 12 weeks. Additionally, world clouds were used for better visualization of various prevalent symptoms.

Results Eighty-two participants were finally included for interview after preliminary screening. Fifty-three patients (64.6%) were male participants; 74.4% had at least one symptom. In general, fatigue, cough, insomnia, and shortness of breath were the most common persistent symptoms. Symptoms were more prevalent among the patients discharged from ICU compared with those discharged from the general ward. Cough, loss of appetite, depression, and incoherence were more common in patients after 12 weeks of hospital discharge.

Conclusion There is a wide range of persistent symptoms in the COVID-19 survivors who have been discharged from the hospital. Some symptoms arise or persisted even after 12 weeks. Based on the study results, available literature, and expert consensus, an assessment form has been developed that could be used for further research and clinical assessment of similar problems. Large-scale epidemiological study (longitudinal and cross-sectional) is needed to understand the nature and prevalence of the postacute phase of COVID-19 at the country level. The results of this study could inform the stakeholders and policymakers for taking necessary steps toward a further decision.

Supplementary Material


Artikel online veröffentlicht:
14. Juni 2022

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  • References

  • 1 Archived: Timeline WHO. - COVID-19 [Internet].. [cited 2021 Jun 22]. Accessed April 20, 2022 from:—covid-19
  • 2 Cascella M, Rajnik M, Aleem A, et al. Features, Evaluation, and Treatment of Coronavirus (COVID-19). In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; [Cited 2021 Nov 16]. Available at:
  • 3 Nalbandian A, Sehgal K, Gupta A. et al. Post-acute COVID-19 syndrome. Nat Med 2021; 27 (04) 601-615
  • 4 Carfì A, Bernabei R, Landi F. Gemelli Against COVID-19 Post-Acute Care Study Group. Persistent symptoms in patients after acute COVID-19. JAMA 2020; 324 (06) 603-605
  • 5 Lopez-Leon S, Wegman-Ostrosky T, Perelman C. et al. More than 50 long-term effects of COVID-19: a systematic review and meta-analysis. Res Sq 2021;
  • 6 Roberts CM, Levi M, McKee M, Schilling R, Lim WS, Grocott MPW. COVID-19: a complex multisystem disorder. Br J Anaesth 2020; 125 (03) 238-242
  • 7 COVID-19 rapid guideline: managing the long-term effects of COVID-19 [Internet].. NICE. [cited 2021 Jun 22]. Accessed April 20, 2022 from:
  • 8 Logue JK, Franko NM, McCulloch DJ. et al. Sequelae in adults at 6 months after COVID-19 infection. JAMA Netw Open 2021; 4 (02) e210830 -undefined.
  • 9 Del Rio C, Collins LF, Malani P. Long-term health consequences of COVID-19. JAMA 2020; 324 (17) 1723-1724
  • 10 Ahmed M, Advani S, Moreira A. et al. Multisystem inflammatory syndrome in children: a systematic review. EClinicalMedicine 2020; 26: 100527
  • 11 Rubens JH, Akindele NP, Tschudy MM, Sick-Samuels AC. Acute covid-19 and multisystem inflammatory syndrome in children. BMJ 2021; 372: n385
  • 12 Multisystem Inflammatory Syndrome in Adults (MIS-A) | CDC [Internet].. [cited 2021 Jun 22]. Accessed April 20, 2022 from:
  • 13 Sudre CH, Murray B, Varsavsky T. et al. Attributes and predictors of long COVID. Nat Med 2021; 27 (04) 626-631
  • 14 Mandal S, Barnett J, Brill SE. et al; ARC Study Group. ‘Long-COVID’: a cross-sectional study of persisting symptoms, biomarker and imaging abnormalities following hospitalisation for COVID-19. Thorax 2021; 76 (04) 396-398
  • 15 Kamal M, Abo Omirah M, Hussein A, Saeed H. Assessment and characterisation of post-COVID-19 manifestations. Int J Clin Pract 2021; 75 (03) e13746