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CC BY-NC-ND 4.0 · J Lab Physicians 2023; 15(01): 045-047
DOI: 10.1055/s-0042-1750076
Original Article

Infection-Related Ventilator-Associated Complication and Possible Ventilator-Associated Pneumonia among Mechanically Ventilated Patients of Adult Medical and Surgical Intensive Care Units

Bijayini Behera 
1   Department of Microbiology, All India Institute of Medical Sciences Bhubaneswar, Bhubaneswar, Odisha, India
,
Ashoka Mahapatra
1   Department of Microbiology, All India Institute of Medical Sciences Bhubaneswar, Bhubaneswar, Odisha, India
,
Jawahar Sreevihar Kunjan Pillai 
2   Department of Hospital Administration, All India Institute of Medical Sciences Bhubaneswar, Bhubaneswar, Odisha, India
,
Jayanti Jena
1   Department of Microbiology, All India Institute of Medical Sciences Bhubaneswar, Bhubaneswar, Odisha, India
,
Jyotirmayee Rath
3   Department of Infection Control Nursing, All India Institute of Medical Sciences Bhubaneswar, Bhubaneswar, Odisha, India
,
Jyotirmayee Biswala
3   Department of Infection Control Nursing, All India Institute of Medical Sciences Bhubaneswar, Bhubaneswar, Odisha, India
,
Chandramani Sahoo
3   Department of Infection Control Nursing, All India Institute of Medical Sciences Bhubaneswar, Bhubaneswar, Odisha, India
,
Rajeswari Panda
3   Department of Infection Control Nursing, All India Institute of Medical Sciences Bhubaneswar, Bhubaneswar, Odisha, India
,
Madhusmita Kanungo
3   Department of Infection Control Nursing, All India Institute of Medical Sciences Bhubaneswar, Bhubaneswar, Odisha, India
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Abstract

Objective An observational study was conducted to evaluate (1) the incidence rates of infection-related ventilator-associated complication (IVAC) and possible ventilator-associated pneumonia (PVAP) among mechanically ventilated patients of adult medical and surgical intensive care units (ICUs) and (2) the pathogen distribution in patients with PVAP.

Materials and Methods The IVAC and PVAP rates of medical and surgical ICUs, between July 1, 2017, and June 30, 2021, per 1,000 mechanical ventilator (MV) days were calculated. The significance of difference in IVAC and PVAP rates between medical and surgical ICUs was calculated. The level of significance was set at less than 0.05.

Results MV utilization ratios of adult medical and surgical ICUs were 0.32 and 0.26, respectively (p < 0.001). About 8 and 7 episodes of IVAC and 14 and 6 episodes of PVAP were reported from adult medical and surgical ICUs, accounting for IVAC rates of 3.17 and 1.8 per 1,000 MV (p > 0.05) and PVAP rates of 2.46 and 1.59 per 1,000 MV days in medical and surgical ICUs, respectively (p > 0.05). Acinetobacter baumannii complex either singly or in combination was isolated in 11/20 PVAP cases.

Conclusion IVAC and PVAP were more in medical compared with surgical ICUs. The most common pathogen in patients with PVAP was A. baumannii complex. More studies are warranted to monitor the significance of ventilator-associated event on patient outcomes.

Keywords

ventilator-associated events - infection -related ventilator-associated complication - possible ventilator-associated pneumonia - Centers for Disease Control and Prevention-National Healthcare Safety Network (CDC-NHSN) - adult medical and surgical intensive care units

Note

The work was presented as chaired poster in the XVII Annual Conference of Hospital Infection Society of India. HISICON 2021. The study was approved by the Institute Ethics Committee, Number T-EM-F/Micro/16/27.


Authors' Contributions

B.B. contributed to the conceptualization, methodology, formal analysis, resources, data curation, writing - original draft, writing - review and editing, supervision, and project administration. A.M. contributed to the data curation, writing - review and editing, supervision, and project administration. J.S.K. contributed to resources, supervision, and project administration. J.J. contributed to methodology and project administration. J.R., J.B., C.S., R.P., and M.K. contributed to formal analysis, data curation, and writing - review and editing.




Publication History

Article published online:
26 July 2022

© 2022. The Indian Association of Laboratory Physicians. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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