Subscribe to RSS
Postoperative Mortality in Surgically Treated Infective Endocarditis Patients and Its Correlation with EuroSCORE I
Introduction Even after advances in medical and surgical treatment, infective endocarditis is associated with substantial morbidity and mortality. The aim of this study was to evaluate postoperative mortality in surgically treated infective endocarditis patients and its correlation with the European System for Cardiac Operative Risk Evaluation (EuroSCORE) I.
Methods This retrospective observational study included 43 patients treated surgically for infective endocarditis, between 2014 and 2019, at a tertiary care center. Mortality in surgically treated infective endocarditis patients was determined in terms of frequency (%). Patients were divided into two groups—survivors and nonsurvivors (died within 30 days of surgery). Mean EuroSCORE I of survivors and nonsurvivors was compared using the unpaired t-test with equal variance. A correlation was sought between mortality and EuroSCORE I as well. The prediction ability of EuroSCORE I for mortality was determined by the area under receiver operating characteristic curve.
Results Out of 43 patients who underwent surgery for infective endocarditis,11 patients (25.58%) died. Mean EuroSCORE I was 15.90 ± 2.02 in nonsurvivors and 7.84 ± 3.19 in survivors. EuroSCORE I was significantly higher in nonsurvivors (p < 0.05). The area under curve value was 0.9744 (p < 0.001), thus showing that EuroSCORE I predicts mortality in surgically treated infective endocarditis patients.
Conclusion The 30-day mortality in patients who underwent surgery for infective endocarditis was 25.58%. There is a significant correlation between EuroSCORE I and mortality. A EuroSCORE I value >14 predicts mortality in surgically treated infective endocarditis patients with sensitivity and specificity of 90.91 and 90.63%, respectively.
Article published online:
01 June 2022
© 2022. Official Publication of The Simulation Society (TSS), accredited by International Society of Cardiovascular Ultrasound (ISCU). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)
Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India
- 1 Kang DH, Kim YJ, Kim SH. et al. Early surgery versus conventional treatment for infective endocarditis. N Engl J Med 2012; 366 (26) 2466-2473
- 2 Gaca JG, Sheng S, Daneshmand MA. et al. Outcomes for endocarditis surgery in North America: a simplified risk scoring system. J Thorac Cardiovasc Surg 2011; 141 (01) 98-106 .e1, 2
- 3 Cahill TJ, Baddour LM, Habib G. et al. Challenges in infective endocarditis. J Am Coll Cardiol 2017; 69 (03) 325-344
- 4 Veloso TR, Que YA, Chaouch A. et al. Prophylaxis of experimental endocarditis with antiplatelet and antithrombin agents: a role for long-term prevention of infective endocarditis in humans?. J Infect Dis 2015; 211 (01) 72-79
- 5 Habib G, Hoen B, Tornos P. et al; ESC Committee for Practice Guidelines; Endorsed by the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) and the International Society of Chemotherapy (ISC) for Infection and Cancer. Guidelines on the prevention, diagnosis, and treatment of infective endocarditis (new version 2009): the Task Force on the Prevention, Diagnosis, and Treatment of Infective Endocarditis of the European Society of Cardiology (ESC). Eur Heart J 2009; 30 (19) 2369-2413
- 6 Patrat-Delon S, Rouxel A, Gacouin A. et al. EuroSCORE II underestimates mortality after cardiac surgery for infective endocarditis. Eur J Cardiothorac Surg 2016; 49 (03) 944-951
- 7 Nashef SA, Roques F, Michel P, Gauducheau E, Lemeshow S, Salamon R. European system for cardiac operative risk evaluation (Euro SCORE). Eur J Cardiothorac Surg 1999; 16 (01) 9-13
- 8 Mokhles MM, Ciampichetti I, Head SJ, Takkenberg JJ, Bogers AJ. Survival of surgically treated infective endocarditis: a comparison with the general Dutch population. Ann Thorac Surg 2011; 91 (05) 1407-1412
- 9 Oliveira JLR, Santos MAD, Arnoni RT. et al. Mortality predictors in the surgical treatment of active infective endocarditis. Rev Bras Cir Cardiovasc 2018; 33 (01) 32-39
- 10 Varela L, López-Menéndez J, Redondo A. et al. Mortality risk prediction in infective endocarditis surgery: reliability analysis of specific scores. Eur J Cardiothorac Surg 2018; 53 (05) 1049-1054
- 11 Di Mauro M, Dato GMA, Barili F. et al; Italian Group of Research for Outcome in Cardiac Surgery (GIROC). A predictive model for early mortality after surgical treatment of heart valve or prosthesis infective endocarditis. The EndoSCORE. Int J Cardiol 2017; 241: 97-102
- 12 Madeira S, Rodrigues R, Tralhão A. et al. Assessment of perioperative mortality risk in patients with infective endocarditis undergoing cardiac surgery: performance of the EuroSCORE I and II logistic models. Interact Cardiovasc Thorac Surg 2016; 22 (02) 141-148