SynOpen, Table of Contents CC BY 4.0 · SynOpen 2023; 07(04): 535-547DOI: 10.1055/s-0042-1751510 paper Virtual Collection Electrochemical Organic Synthesis Oxidative C–H Sulfonylation of Hydrazones Enabled by Electrochemistry Authors Qi-Liang Yang ∗ Ping-Ping Lei‡ Er-Jun Hao Bei-Ning Zhang Hong-Hao Zhou Wan-Wan Li Hai-Ming Guo∗ Recommend Article Abstract All articles of this category(opens in new window) Abstract An efficient electrochemical oxidative C(sp2)–H sulfonylation of aldehyde hydrazones is described. A variety of sodium sufinates or sulfinic acids participate effectively in this protocol, which provides facile access to an array of alkyl and aromatic sulfonylated hydrazones with up to 96% yield. Large-scale synthesis and product derivatization show the potential utility of this methodology. Preliminary mechanistic investigations including radical-inhibition, electricity on/off experiments, and cyclic voltammetry support a radical pathway. 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