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CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2022; 43(05): 404-408
DOI: 10.1055/s-0042-1755596
Original Article

Quality of Life and Limb Functionality in Adolescents and Young Adults Surviving Bone Tumors in the Lower Extremity in a Developing Country: A Cross-Sectional Study

Liliana Vasquez
1   Faculty of Medicine, University of San Martin de Porres, Research Center of Precision Medicine, Lima, Peru
,
Mariela Tello
2   Department of Pediatric and Adolescent Oncology, Rebagliati Hospital, Essalud, Lima, Peru
,
Ivan Maza
2   Department of Pediatric and Adolescent Oncology, Rebagliati Hospital, Essalud, Lima, Peru
,
Darshi Shah
3   Department of Biomedical Engineering, Boston University, Boston, Massachusetts, United States of America
,
Jose Silva
4   Orthopedic Oncology Division, Rebagliati Hospital, Essalud, Lima, Peru
,
Luis Sialer
4   Orthopedic Oncology Division, Rebagliati Hospital, Essalud, Lima, Peru
› Author Affiliations Funding None.
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Abstract

Introduction Due to higher survival rates among patients with bone tumors, there is a growing interest in determining these individuals' limb functionality and psychosocial prognosis.

Objectives This study aimed to analyze the differences in functionality and quality of life (QoL) related to health in patients diagnosed with a malignant bone tumor during childhood, according to the type of surgery performed.

Materials and Methods A cross-sectional study was performed for patients older than 14 years who treated for osteosarcoma or Ewing's sarcoma of the lower limb by who receiving surgery. To assess lower limb functionality and QoL among patients surviving malignant bone tumors, 19 patients surviving osteosarcoma or Ewing's sarcoma of the lower extremity were studied. An evaluation of functionality and QoL was done using the “Enneking and Medical Outcomes Study Short-Form 36 scales.” We compared the functional results according to the surgical technique used. Categorical variables were compared according to the Mann–Whitney and Kruskal–Wallis tests, with an established 95% level of significance.

Results QoL among patients who had conservative surgery was not significantly better than amputee patients in the physical or mental aspects, nor in any of their components. Limb functionality, according to Enneking's staging, was significantly higher in non-amputee patients (p = 0.035).

Conclusion According to the data analysis done in this study, the QoL was found to be not significantly different, based on the type of surgery performed; however, there were differences in limb functionality.

Keywords

survivorship - quality of life - osteosarcoma - Ewing's sarcoma

Supplementary Material



Publication History

Article published online:
20 October 2022

© 2022. Indian Society of Medical and Paediatric Oncology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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