Subscribe to RSS
Download PDF
DOI: 10.1055/s-0042-1757962
An Atypical Cause of a Child Limp: A Gorham-Stout Disease with a Vanishing Hip
Article in several languages: português | EnglishFinancial Support The present study received no financial support from either public, commercial, or not-for-profit sources.
Abstract
Gorham-Stout disease (GSD) is a rare bone disease characterized by an abnormal proliferation of endothelial-lined vessels and destruction of the affected bone. As it affects commonly children and young adults, it is associated with significant morbidity and mortality. To date, there is no established treatment strategy for GSD.
We report through this observation a rare case of GSD in a child located in the hip and the iliac crest.
Study carried out the Kassab Orthopedics Institute, Rheumatology Department, Ksar Saïd, Tunisia; University Tunis el Manar, Faculty of Medicine, Tunis, Tunisia.
Publication History
Received: 12 July 2022
Accepted: 15 September 2022
Article published online:
31 July 2023
© 2023. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution 4.0 International License, permitting copying and reproduction so long as the original work is given appropriate credit (https://creativecommons.org/licenses/by/4.0/)
Thieme Revinter Publicações Ltda.
Rua do Matoso 170, Rio de Janeiro, RJ, CEP 20270-135, Brazil
-
Referências
- 1 Li MH, Zhang HQ, Lu YJ. et al. Successful Management of Gorham-Stout Disease in Scapula and Ribs: A Case Report and Literature Review. Orthop Surg 2018; 10 (03) 276-280
- 2 Saify FY, Gosavi SR. Gorham's disease: A diagnostic challenge. J Oral Maxillofac Pathol 2014; 18 (03) 411-414
- 3 Schneider KN, Masthoff M, Gosheger G. et al. Gorham-Stout disease: good results of bisphosphonate treatment in 6 of 7 patients. Acta Orthop 2020; 91 (02) 209-214
- 4 Takaya K, Sakamoto Y, Miwa T, Yoshida K, Kishi K. Gorham-Stout disease with parietal bone osteolysis: a case series and review of literature. Br J Neurosurg 2021; 35 (01) 27-31
- 5 Vaishya R, Vaish A, Singh LK, Baweja P. Management of a pathological fracture in a rare case of Gorham Stout disease of the hip with a mega prosthesis. J Orthop 2019; 18: 177-180
- 6 Dellinger MT, Garg N, Olsen BR. Viewpoints on vessels and vanishing bones in Gorham-Stout disease. Bone 2014; 63: 47-52
- 7 Albuquerque RJ, Hayashi T, Cho WG. et al. Alternatively spliced vascular endothelial growth factor receptor-2 is an essential endogenous inhibitor of lymphatic vessel growth. Nat Med 2009; 15 (09) 1023-1030
- 8 Fretz CJ, Jungi WF, Neuweiler J, Haertel M. [The malignant degeneration of Gorham-Stout disease?]. Röfo Fortschr Geb Röntgenstr Nuklearmed 1991; 155 (06) 579-581
- 9 Jagtap R, Alansari R, Ruprecht A, Kashtwari D. Trichodentoosseous syndrome: a case report and review of literature. BJR Case Rep 2019; 5 (04) 20190039
- 10 Ricci KW, Hammill AM, Mobberley-Schuman P. et al. Efficacy of systemic sirolimus in the treatment of generalized lymphatic anomaly and Gorham-Stout disease. Pediatr Blood Cancer 2019; 66 (05) e27614