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CC BY-NC-ND 4.0 · J Lab Physicians
DOI: 10.1055/s-0042-1758662
Brief Report

Seropositivity Pattern of Human Cystic Echinococcosis at a Tertiary Care Hospital of India

Rojaleen Das 
1   Department of Microbiology, All India Institute of Medical Sciences, New Delhi, India
,
Varuna Gupta
1   Department of Microbiology, All India Institute of Medical Sciences, New Delhi, India
,
Swati Khullar
1   Department of Microbiology, All India Institute of Medical Sciences, New Delhi, India
,
Nishant Verma
1   Department of Microbiology, All India Institute of Medical Sciences, New Delhi, India
,
Bijay Ranjan Mirdha
1   Department of Microbiology, All India Institute of Medical Sciences, New Delhi, India
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Abstract

Cystic echinococcosis (CE), even after several control measures, causes significant morbidity throughout the world. Besides imaging investigation technology, the serological tests are essential for both diagnosis and management of this slowly progressive disease. The present study was a hospital-based retrospective study that examined the seropositivity rate for Echinococcus granulosus sensu lato antibody in patients suspected of CE at our tertiary health care center over 8 years from 2013 to 2020. Records of new visits to hospital/clinics and associated hospital discharge constituted the denominator of calculation. All samples were tested using commercially available indirect immunoglobulin G enzyme-linked immunosorbent assay kit. A total of 925 suspected patients with a clinical diagnosis of CE were screened. The age group that commonly tested positive for CE was 20 to 39 years, and liver was the predominant organ found to be affected. The seropositive rate was 41.2%. On further year-wise analysis, it was observed that the seropositivity rate had significantly declined from 61.4% in 2013 to 33.8% in 2020. This study clearly showed that there is a by 27.6% decline of CE seropositivity rate in 8 years. This declining rate may be attributed to improved socioeconomic status and better implementation of health programs.

Keywords

echinococcus granulosus - ELISA - seropositivity rate - hospital - cystic echinococcosis

Authors' Contribution

R.D. contributed to writing the manuscript, and analysis and interpretation of the data; V.G. and S.K. in collection and analysis of the data; N.V. in review and edit of the manuscript; and B.R.M. in concept designing and final editing the manuscript.




Publication History

Article published online:
06 February 2023

© 2023. The Indian Association of Laboratory Physicians. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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