COVID-19 Vaccines—All You Want to Know

Akira A. Shishido; Ashley H. Barnes; Shivakumar Narayanan; Joel V. Chua

doi:10.1055/s-0042-1759779

Seminars in Respiratory and Critical Care Medicine, Inhaltsverzeichnis

Semin Respir Crit Care Med 2023; 44(01): 143-172
DOI: 10.1055/s-0042-1759779

Review Article

COVID-19 Vaccines—All You Want to Know

Authors

Akira A. Shishido

¹Division of Clinical Care and Research, Institute of Human Virology, University of Maryland School of Medicine, Baltimore, Maryland

²Division of Infectious Diseases, Virginia Commonwealth University, Richmond, Virginia
Ashley H. Barnes

¹Division of Clinical Care and Research, Institute of Human Virology, University of Maryland School of Medicine, Baltimore, Maryland
Shivakumar Narayanan

¹Division of Clinical Care and Research, Institute of Human Virology, University of Maryland School of Medicine, Baltimore, Maryland
Joel V. Chua

¹Division of Clinical Care and Research, Institute of Human Virology, University of Maryland School of Medicine, Baltimore, Maryland

Abstract

The severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) pandemic has led to an unprecedented public health crisis. The collective global response has led to production of multiple safe and effective vaccines utilizing novel platforms to combat the virus that have propelled the field of vaccinology forward. Significant challenges to universal vaccine effectiveness remain, including immune evasion by SARS-CoV-2 variants, waning of immune response, inadequate knowledge of correlates of protection, and dosing in special populations. This review serves as a detailed evaluation of the development of the current SARS-CoV-2 vaccines, their effectiveness, and challenges to their deployment as a preventive tool.

Keywords

COVID-19 - SARS-CoV-2 - vaccines - variants - immunity

Volltext

Referenzen

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