CC BY-NC-ND 4.0 · Journal of Cardiac Critical Care TSS 2022; 06(03): 222-224
DOI: 10.1055/s-0042-1759811
Case Report

Heparin-Induced Fever in a Cardiac Transplant Candidate

Payal Rohit Patel
1   Department of Internal Medicine, Washington University in Saint Louis/Barnes-Jewish Hospital, Saint Louis, Missouri, United States
,
Bria Giacomino
2   Department of Cardiology, Washington University in Saint Louis, Saint Louis, Missouri, United States
› Author Affiliations
Funding None.

Abstract

Patient admitted to intensive care units frequently have fevers. A less common cause for fever is a drug-induced fever. For patients who are candidates for heart transplantation, persistent fevers can place a hold on their transplant candidacy until the etiology is found and the fevers resolve. We present a case of a patient with dilated cardiomyopathy who experienced fevers thought secondary to heparin that improved only with discontinuation of therapy and later underwent successful heart transplantation. Only three prior case reports of heparin-induced fevers are currently described in literature.



Publication History

Article published online:
03 December 2022

© 2022. Official Publication of The Simulation Society (TSS), accredited by International Society of Cardiovascular Ultrasound (ISCU). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India

 
  • References

  • 1 Dimopoulos G, Falagas ME. Approach to the febrile patient in the ICU. Infect Dis Clin North Am 2009; 23 (03) 471-484
  • 2 Dibyendu Banerjee, Tanushree Banerjee, Vivek Vidyadhar Bhosale. Approach to Managing Febrile Patients in the ICU. Gen Med (Los Angeles) 2016; 4 (05) 274
  • 3 Patel RA, Gallagher JC. Drug fever. Pharmacotherapy 2010; 30 (01) 57-69
  • 4 Laun J, Laun K, Farooqi A, Smith DJ. Heparin-induced fever: a case report and literature review. J Burn Care Res 2019; 40 (05) 723-724
  • 5 Krishnakumar M, Naik SS, Ramesh VJ, Mouleeswaran S. Heparin-induced fever in neurointensive care unit: a rarity yet a possibility. J Neuroanaesth Crit Care 2022; 09: 53-55
  • 6 Forni AL, Murray HW. Drug fever induced by heparin. Am J Med 1992; 92 (01) 107
  • 7 Ye F, Hatahet M, Youniss MA, Toklu HZ, Mazza JJ, Yale S. The clinical significance of relative bradycardia. WMJ 2018; 117 (02) 73-78
  • 8 Bowers RD, Nowak J, Bryan D, Biondi N, Dorsett B. Utilization of a dextrose-only purge solution for an LVAD in patients with suspected HIT: a case series. J Pharm Pract 2021; 34 (06) 966-969
  • 9 Costanzo MR, Dipchand A, Starling R. et al; International Society of Heart and Lung Transplantation Guidelines. The International Society of Heart and Lung Transplantation Guidelines for the care of heart transplant recipients. J Heart Lung Transplant 2010; 29 (08) 914-956
  • 10 Malinis M, Boucher HW. AST Infectious Diseases Community of Practice. Screening of donor and candidate prior to solid organ transplantation-guidelines from the American Society of Transplantation Infectious Diseases Community of Practice. Clin Transplant 2019; 33 (09) e13548