Semin Musculoskelet Radiol 2022; 26(06): 710-716
DOI: 10.1055/s-0042-1760212
Review Article

Presurgical Perspective and Postsurgical Evaluation of Morton's Neuroma and Other Nerve Lesions

Marco Zanetti
1   Centre of Musculoskeletal Radiology, Radiology Department, Clinic Hirslanden, Zurich, Switzerland
,
Nadja Saupe
1   Centre of Musculoskeletal Radiology, Radiology Department, Clinic Hirslanden, Zurich, Switzerland
› Author Affiliations

Abstract

Magnetic resonance imaging (MRI) is a robust method used for both preoperative and postoperative evaluation of Morton's neuroma and other neural lesions. MRI is used to confirm the diagnosis and for precise localization, estimation of outcome, and differential diagnoses. The differential diagnoses include mechanically induced plantar plate ruptures with associated Morton's neuroma–like tumors in the intermetatarsal/interdigital spaces; mechanical fibrosis cushion formations and pseudo bursae in the plantar foot adipose tissue; rheumatologic affections, such as rheumatoid nodules, gouty nodules, and intermetatarsal bursitis; and lastly the tenosynovial giant cell tumor (formerly called pigmented villonodular synovitis). In the postoperative evaluation after resection of Morton's neuroma, the same differential diagnoses must be considered as in the preoperative evaluation. Similarly, a high prevalence (up to 25%) of asymptomatic Morton's neuroma–like findings in the intermetatarsal and interdigital spaces should be kept in mind when interpreting postoperative recurrent forefoot pain after Morton's neuroma resection.



Publication History

Article published online:
15 February 2023

© 2023. Thieme. All rights reserved.

Thieme Medical Publishers, Inc.
333 Seventh Avenue, 18th Floor, New York, NY 10001, USA

 
  • References

  • 1 Zanetti M, Strehle JK, Kundert H-P, Zollinger H, Hodler J. Morton neuroma: effect of MR imaging findings on diagnostic thinking and therapeutic decisions. Radiology 1999; 213 (02) 583-588
  • 2 Bignotti B, Signori A, Sormani MP, Molfetta L, Martinoli C, Tagliafico A. Ultrasound versus magnetic resonance imaging for Morton neuroma: systematic review and meta-analysis. Eur Radiol 2015; 25 (08) 2254-2262
  • 3 Galley J, Sutter R, Germann C, Pfirrmann CWA. The Vulcan salute sign: a non-sensitive but specific sign for Morton's neuroma on radiographs. Skeletal Radiol 2022; 51 (03) 581-586
  • 4 Mann TS, Nery C, Baumfeld D, Fernandes EA. Is second metatarsal protrusion related to metatarsophalangeal plantar plate rupture?. AJR Am J Roentgenol 2021; 216 (01) 132-140
  • 5 Zanetti M, Ledermann T, Zollinger H, Hodler J. Efficacy of MR imaging in patients suspected of having Morton's neuroma. AJR Am J Roentgenol 1997; 168 (02) 529-532
  • 6 Biasca N, Zanetti M, Zollinger H. Outcomes after partial neurectomy of Morton's neuroma related to preoperative case histories, clinical findings, and findings on magnetic resonance imaging scans. Foot Ankle Int 1999; 20 (09) 568-575
  • 7 Weishaupt D, Treiber K, Jacob HAC. et al. MR imaging of the forefoot under weight-bearing conditions: position-related changes of the neurovascular bundles and the metatarsal heads in asymptomatic volunteers. J Magn Reson Imaging 2002; 16 (01) 75-84
  • 8 Zanetti M, Strehle JK, Zollinger H, Hodler J. Morton neuroma and fluid in the intermetatarsal bursae on MR images of 70 asymptomatic volunteers. Radiology 1997; 203 (02) 516-520
  • 9 Bencardino J, Rosenberg ZS, Beltran J, Liu X, Marty-Delfaut E. Morton's neuroma: is it always symptomatic?. AJR Am J Roentgenol 2000; 175 (03) 649-653
  • 10 Umans H, Wilde G, Morrison W, Elsinger E. The role of intravenous gadolinium in diagnosis of metatarsophalangeal joint plantar plate and capsular tears. Skeletal Radiol 2014; 43: 1803-1804
  • 11 Dinoá V, von Ranke F, Costa F, Marchiori E. Evaluation of lesser metatarsophalangeal joint plantar plate tears with contrast-enhanced and fat-suppressed MRI. Skeletal Radiol 2016; 45 (05) 635-644
  • 12 Studler U, Mengiardi B, Bode B. et al. Fibrosis and adventitious bursae in plantar fat pad of forefoot: MR imaging findings in asymptomatic volunteers and MR imaging-histologic comparison. Radiology 2008; 246 (03) 863-870
  • 13 Boutry N, Flipo RM, Cotten A. MR imaging appearance of rheumatoid arthritis in the foot. Semin Musculoskelet Radiol 2005; 9 (03) 199-209
  • 14 Razaghi F, Abyar E, Cignetti CA. et al. A case of a second intermetatarsal space gouty tophus with a presentation similar to a Morton's neuroma. Cureus 2018; 10 (05) e2620
  • 15 Jelinek JS, Kransdorf MJ, Shmookler BM, Aboulafia AA, Malawer MM. Giant cell tumor of the tendon sheath: MR findings in nine cases. AJR Am J Roentgenol 1994; 162 (04) 919-922
  • 16 Le Corroller T, Santiago E, Deniel A, Causeret A, Champsaur P, Guillin R. Anatomical study of the medial plantar proper digital nerve using ultrasound. Eur Radiol 2019; 29 (01) 40-45
  • 17 Woertler K. Tumors and tumor-like lesions of peripheral nerves. Semin Musculoskelet Radiol 2010; 14 (05) 547-558
  • 18 Espinosa N, Schmitt JW, Saupe N. et al. Morton neuroma: MR imaging after resection–postoperative MR and histologic findings in asymptomatic and symptomatic intermetatarsal spaces. Radiology 2010; 255 (03) 850-856