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Int J Sports Med 2017; 38(05): 396-401
DOI: 10.1055/s-0043-101676
Behavioural Sciences
© Georg Thieme Verlag KG Stuttgart · New York

Sedentary Behavior and Arterial Stiffness in Adults with and without Metabolic Syndrome

Lucimere Bohn
1   Research Center in Physical Activity, Health and Leisure, Faculty of Sport, University of Porto, Porto, Portugal
,
Ana Ramoa
1   Research Center in Physical Activity, Health and Leisure, Faculty of Sport, University of Porto, Porto, Portugal
,
Gustavo Silva
1   Research Center in Physical Activity, Health and Leisure, Faculty of Sport, University of Porto, Porto, Portugal
,
Nuno Silva
2   Department of Biochemistry, Porto, University of Porto Faculty of Medicina, Portugal
,
Sandra Marlene Abreu
3   Education and Sport, Faculty of Psychology, Lusófona University of Porto, Porto, Portugal
,
Fernando Ribeiro
4   School of Health Sciences and Institute of Biomedicine- iBiMED, University of Aveiro, Aveiro, Portugal
,
Pierre Boutouyrie
5   Pharmacology Department and INSERM U 970, Hopital Europeen Georges Pompidou, Paris, France
,
Stéphane Laurent
5   Pharmacology Department and INSERM U 970, Hopital Europeen Georges Pompidou, Paris, France
,
José Oliveira
1   Research Center in Physical Activity, Health and Leisure, Faculty of Sport, University of Porto, Porto, Portugal
› Author Affiliations
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Publication History



accepted after revision 26 October 2016

Publication Date:
09 May 2017 (online)

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Abstract

This study aimed to investigate whether sedentary time (Sed) and physical activity (PA) are associated with arterial stiffness in individuals with and without metabolic syndrome (MetS). This cross-sectional study comprised 197 individuals (47±13 years; 58% female) from a primary health care centre. Arterial stiffness was assessed using carotid-femoral pulse wave velocity (cfPWV). Metabolic syndrome was determined as clustering of at least 3 out of 5 risk factors (central obesity, hypertension, impaired glucose, triglycerides and high-density lipoprotein cholesterol). Daily PA was objectively assessed and classified in Sed, light and moderate-to-vigorous PA. Physical activity was used as a continuous variable for multiple regression analysis. For mean comparisons of cfPWV between subjects with and without MetS, a binary split at the median of Sed and PA was used. Sedentary time was associated with cfPWV (β=0.11; p=0.01) explaining 1.3% of its variance; independently of age (β=0.49; p<0.001), systolic blood pressure (β=0.27; p<0.001) and fasting glucose (β=0.19; p<0.001). Participants with MetS and more Sed had higher cfPWV than those with MetS and less Sed (9.9±1.0 vs. 8.9±1.0 m/s; p<0.05). Sedentary time is associated with cfPWV independently of age and metabolic risk factors. A higher Sed in MetS individuals lead to a worse arterial stiffness profile.

Key word

pulse wave velocity - physical activity - sedentary behaviour - metabolic syndrome
 

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