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CC BY-NC-ND 4.0 · Geburtshilfe Frauenheilkd 2017; 77(12): 1299-1303
DOI: 10.1055/s-0043-119687
GebFra Science
Review/Übersicht
Georg Thieme Verlag KG Stuttgart · New York

A Systematic Review of Mycoplasma and Ureaplasma in Urogynaecology

Article in several languages: English | deutsch
Nina Combaz-Söhnchen
1   Abteilung Frau und Kind, Spital Sitten, Sitten, Schweiz
,
Annette Kuhn
2   Urogynäkologie Frauenklinik, Inselspital, Bern, Schweiz
› Author Affiliations
Further Information

Publication History

received 01 July 2017
revised 12 September 2017

accepted 13 September 2017

Publication Date:
18 December 2017 (online)

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Abstract

Mycoplasma species relevant to the urogenital tract include mycoplasma hominis, mycoplasma genitalia and ureaplasma urealyticum. Their occurrence in the context of urogynaecological disease has been demonstrated in urethritis, cystitis and upper renal tract infections. Their role in hyperactive bladder and interstitial cystitis/painful bladder syndrome is controversial. All the above-mentioned microorganisms can occur as commensals or as potential pathogens. In most cases their role in any particular pathology cannot be proven, only presumed. The aim of this systematic review was to summarise current knowledge on the influence of mycoplasma and ureaplasma in urogynaecological pathology and to provide clinical guidance on diagnosis (when and how is pathogen detection indicated?) and treatment. 377 relevant articles were analysed. In summary: a urethral swab for PCR analysis of the three bacteria should be performed in the context of symptomatic sterile leukocyturia, chronic urethritis and suspected hyperactive bladder or interstitial cystitis/painful bladder syndrome. Symptomatic women should be treated strictly according to results of the antibiogram.

Key words

mycoplasma - ureaplasma - hyperactive bladder - bladder pain syndrome - infections in urogynaecology
 

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