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CC BY-NC-ND 4.0 · Ann Natl Acad Med Sci 2023; 59(02): 090-096
DOI: 10.1055/s-0043-1764349
Original Article

Evaluation of Clinical, Demographic, and Biochemical Profiles of Trinidadian Patients Undergoing Coronary Angiography

Shivananda Nayak B
1   Department of Preclinical Sciences, The University of the West Indies, Faculty of Medical Sciences, Trinidad and Tobago, West Indies
,
Tamika Kachada Monplaisir
2   Department of Pre-Clinical Sciences, Faculty of Medical Sciences, The University of the West Indies, St. Augustine, Trinidad and Tobago
,
Geetha Bhaktha
3   Multidisciplinary Research Unit, Shimoga Institute of Medical Sciences, Shivamogga, Karnataka, India
,
Ronan Ali 
4   Department Adult Medicine Unit, Department of Clinical Medical Sciences, The University of the West Indies, St. Augustine, Trinidad and Tobago
,
Surapaneni Krishna Mohan 
5   Department of Biochemistry, Panimalar Medical College Hospital & Research Institute, Varadharajapuram, Poonamallee, Chennai, Tamil Nadu, India
,
Vishnu Priya
6   Department of Biochemistry, Saveetha University, Chennai, Tamil Nadu, India
› Author Affiliations Funding The authors would like to thank Campus Research and Publication fund, The University of the West Indies for providing the grant to conduct this study.
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Abstract

Background Trinidad and Tobago ranks number 45 in the world for total deaths due to coronary heart disease. Predictive tests for coronary angiographic results set the basis for earlier monitoring of the disease before additional complications become obvious.

Aims and Methods This study aimed to evaluate the anthropometric and biochemical parameters of 124 patients with suspected coronary artery disease (CAD) in Trinidad and how these parameters correlate to the findings at angiography.

Results The biochemical parameters showed statistically significant correlations with CAD severity by Spearman's rank-order correlation. Two clinical parameters showed significant associations with CAD severity—ethnicity (χ2 (4) = 12.925, p = 0.012) and presence of type 2 diabetes at baseline (χ2 (4) = 21.483, p < 0.001).

Conclusion Biochemical parameters such as fasting blood sugar, N-terminal pro B-type natriuretic peptide, creatinine, and hemoglobin A1c were well correlated and well associated with the severity of CAD after diagnosis by the process of coronary angiography. Hence, these factors can be taken into consideration to predict the severity of CAD.

Keywords

coronary angiography - coronary artery disease - glycated hemoglobin - diabetes mellitus - NT-proBNP


Publication History

Article published online:
12 April 2023

© 2023. National Academy of Medical Sciences (India). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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