Right-sided facial pain as a nonspecific initial symptom of a life-threatening disease

Introduction Orofacial mucormycosis as an invasive fungal infection can affect different intra- and extracranial localizations depending on its severity. As a rare but life-threatening disease, it is important for every physician to acknowledge mucormycosis and to initiate an adequate therapy immediately.

Results A 56-year-old patient came to the university hospital emergency room with nonspecific left-sided facial pain and progressive cephalgia in May 2021. MRI and CT revealed an extensive phlegmonous process of the infratemporal and pterygopalatine fossae. The diagnosis of mucormycosis was confirmed by intraoperative swabbing and tissue sampling. Repeated consistent surgical drainage as well as intravenous administration of amphotericin B over a period of four months were performed. Residual symptoms are still present today.

Discussion Diagnostic and therapeutic steps are outlined, and the course of treatment and – long-term follow-up are described. The case report illustrates how difficult the correct diagnosis can be and yet, with consistent implementation of the therapy regimem cure is possible

Publication History

Article published online:
27 June 2023