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CC BY-NC-ND 4.0 · Indian J Plast Surg 1987; 20(01): 013-017
DOI: 10.1055/s-0043-1772535
Review Article

Role of Aprotinin in Moderate and Severe Burns

Authors

  • Prateek Bhatnagar

  • A. K. Singh

  • Tarachand Tarachand

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Summary

The role of Aprotinin (Antagosan) in moderate and severe thermal burns has been studied. Patients were randomized in two groups; both receiving same treatment with the exception that patients in trial group received Aprotinin in addition. 2000,000 K.I.U. (Kallikrein inhibition units) Aprotinin was given I.V. stat, followed six hourly, for three days. Mortality was 27.08 percent in trial group and 47.9 percent in control group (p < 0.05). Aprotinin is believed to be helpful in reducing mortality in burns.



Publication History

Article published online:
08 August 2023

© 2023. Association of Plastic Surgeons of India. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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