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CC BY-NC-ND 4.0 · J Lab Physicians
DOI: 10.1055/s-0043-1772851
Case Reports

Metastasis of Maxillary Sinus Adenoid Cystic Carcinoma to the Humerus Bone—A Rare Case Report

Mala Sagar
1   Department of Pathology, King George Medical University, Lucknow, Uttar Pradesh, India
,
Anurag Singh
1   Department of Pathology, King George Medical University, Lucknow, Uttar Pradesh, India
,
Sumairya Qayoom
1   Department of Pathology, King George Medical University, Lucknow, Uttar Pradesh, India
,
U. S. Singh
1   Department of Pathology, King George Medical University, Lucknow, Uttar Pradesh, India
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Abstract

Adenoid cystic carcinoma accounts for 10 to 12% of all salivary gland malignant neoplasms with an estimated incidence of 3 to 4.5 cases per million per year. Perineural spread and multiple local recurrences are its defining features, although the liver and lung are the most frequent sites for distant metastases. It is extremely uncommon for adenoid cystic carcinoma of the maxillary sinus to spread to distant bones. Few cases of adenoid cystic carcinoma with distant bone metastasis have been reported. Here, we report a known case of the adenoid cystic carcinoma of the maxillary sinus in a 40-year-old male, with isolated metastasis to the left humerus bone presenting 4 years later to the excision of the primary lesion. The fine-needle aspiration cytology, trucut biopsy, and immunocytochemistry of the left humerus osteoexpansile lesion confirmed the diagnosis of metastatic adenoid cystic carcinoma. This rare case report re-emphasizes the distant metastatic potential of adenoid cystic carcinoma.

Keywords

adenoid cystic carcinoma - humerus bone - maxillary sinus - metastasis

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Ethical Clearance

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Publication History

Received: 29 December 2022

Accepted: 01 March 2023

Article published online:
28 August 2023

© 2023. The Indian Association of Laboratory Physicians. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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