Case Report: Periosteal Ewing's sarcoma of the proximal humerus

Abstract

Ewing's sarcoma is the third most common malignant bone tumor, occurring in patients under 20 years of age in 80% of cases. Histologically it is composed of small round cells with round nuclei with chromatin and eosinophilic cytoplasm. For its definitive diagnosis, a molecular study is necessary. It classically affects the medullary cavity of the diaphysis of long bones, however, it has less frequent presentations such as the extra osseous and the periosteal. We present a case report of a 17-year-old patient with swelling in the left proximal humerus with imaging studies compatible with a periosteal tumor lesion that spares the medullary cavity. A biopsy of the tumor was performed with histopathological and molecular confirmation of Ewing's sarcoma, which was treated with concomitant chemotherapy and radiotherapy, obtaining a progressive decrease in the size of the lesion and therefore surgery was not necessary. Periosteal Ewing's sarcoma is an extremely unusual entity, with few cases reported in the literature, which makes it important to recognize and treat these aggressive bone lesions in a timely manner.

Keywords

ewing's sarcoma - parostal ewing's sarcoma - periostal ewing's sarcoma - sarcoma - bone tumor

Publikationsverlauf

Eingereicht: 11. November 2022

Angenommen: 14. August 2023

Artikel online veröffentlicht:
30. Oktober 2023

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