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CC BY 4.0 · Avicenna J Med 2023; 13(04): 247-252
DOI: 10.1055/s-0043-1775997
Case Report

Primary Sarcomas of the Larynx: A Case Series of Four Different Histopathologic Types

Ala S. Abu-Dayeh 
1   Division of Anatomic Pathology, Hamad Medical Corporation, Doha 576214, Qatar
,
Khaled A. Murshed
1   Division of Anatomic Pathology, Hamad Medical Corporation, Doha 576214, Qatar
,
Adham Ammar
1   Division of Anatomic Pathology, Hamad Medical Corporation, Doha 576214, Qatar
,
Mahir Petkar 
1   Division of Anatomic Pathology, Hamad Medical Corporation, Doha 576214, Qatar
› Author Affiliations
Funding No funding was received.
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Abstract

Primary laryngeal sarcomas are rare. Their nomenclature and classification are similar to soft tissue counterparts; however, there are notable differences between clinical presentation, behavior, treatment, and follow-up. There is sparse information regarding the clinical features, biologic behavior, and treatment modalities of laryngeal sarcomas. To increase our understanding about these tumors, we describe herein an additional series of four cases of different pathologic types of laryngeal sarcomas, including low-grade chondrosarcoma, leiomyosarcoma, well-differentiated liposarcoma, and undifferentiated pleomorphic sarcoma. Our main aim is to upsurge awareness about the morphologic variations of laryngeal sarcomas, to avoid potential pitfalls during histopathologic examination. It is essential to ensure that correct diagnosis, subclassification, and grading are achieved for proper guidance of treatment and clinical follow-up at multidisciplinary team meetings.

Keywords

larynx - sarcoma - chondrosarcoma - leiomyosarcoma - liposarcoma - undifferentiated pleomorphic sarcoma

Consent to Publish

Informed consent from the participant has been waived by Institutional Review Board.


Ethical Approval

The Institutional Review Board at Hamad Medical Corporation approved publication of this article under the number (MRC-04–21–908).


Data Availability Statement

The data that support the findings of this study are available from the corresponding author upon reasonable request.


*These authors contributed equally.




Publication History

Article published online:
11 December 2023

© 2023. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

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